Filing Details

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Number of

Shares

Beneficially

Owned by

Each

Reporting

Person

With:

Sole Voting Power

0 shares

Shared Voting Power

899,700 shares

Sole Dispositive Power

0 shares

Shared Dispositive Power

899,700 shares

Accession Number:: 0001193125-20-296896
Form Type:: 13D Filing
Publication Date:: 2020-11-18 15:35:52

Filed By:: Frazier Healthcare V, Lp
Company:: Anaptysbio Inc (NASDAQ:ANAB)
Filing Date:: 2020-11-18
SEC Url:: 13D Filing

Ownership Summary

Please notice the below summary table is generated without human intervention and may contain errors. Please refer to the complete filing displayed below for exact figures.

Name	Sole Voting Power	Shared Voting Power	Sole Dispositive Power	Shared Dispositive Power	Aggregate Amount Owned Power	Percent of Class
Frazier Healthcare V	0	899,700	0	899,700	899,700	3.3%
FHM V	0	899,700	0	899,700	899,700	3.3%
FHM V	0	899,700	0	899,700	899,700	3.3%
Frazier Healthcare VII	0	899,700	0	899,700	899,700	3.3%
Frazier Healthcare VII-A	0	899,700	0	899,700	899,700	3.3%
FHM VII	0	899,700	0	899,700	899,700	3.3%
FHM VII	0	899,700	0	899,700	899,700	3.3%
James N. Topper	117,895	899,700	117,895	899,700	1,017,595	3.7%
Patrick J. Heron	0	899,700	0	899,700	899,700	3.3%
Alan Frazier	0	899,700	0	899,700	899,700	3.3%
Nader Naini	0	899,700	0	899,700	899,700	3.3%
Nathan Every	0	899,700	0	899,700	899,700	3.3%
Brian Morfitt	0	899,700	0	899,700	899,700	3.3%

Filing

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

SCHEDULE 13D

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 4)*

AnaptysBio, Inc.

(Name of Issuer)

Common Stock, $0.001 par value per share

(Title of Class of Securities)

032724106

(CUSIP Number)

Steve R. Bailey

Frazier Healthcare Partners

601 Union Street, Suite 3200

Seattle, WA 98101

Telephone: (206) 621-7200

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

November 16, 2020

(Date of Event Which Requires Filing of This Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ☐

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties to whom copies are to be sent.

*	The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be filed for the purpose of Section 18 of the Securities Exchange Act of 1934 (Act) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).


CUSIP No. 032724106


1.		Name of Reporting Persons. Frazier Healthcare V, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) WC
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 2


CUSIP No. 032724106


1.		Name of Reporting Persons. FHM V, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 3


CUSIP No. 032724106


1.		Name of Reporting Persons. FHM V, L.L.C.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 4

CUSIP No. 032724106


1.		Name of Reporting Persons. Frazier Healthcare VII, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) WC
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 5

CUSIP No. 032724106


1.		Name of Reporting Persons. Frazier Healthcare VII-A, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 6

CUSIP No. 032724106


1.		Name of Reporting Persons. FHM VII, L.P.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 7

CUSIP No. 032724106


1.		Name of Reporting Persons. FHM VII, L.L.C.
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization Delaware

Page 8

CUSIP No. 032724106


1.		Name of Reporting Persons. James N. Topper
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization United States Citizen

Page 9

CUSIP No. 032724106


1.		Name of Reporting Persons. Patrick J. Heron
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization United States Citizen

Page 10

CUSIP No. 032724106


1.		Name of Reporting Persons. Alan Frazier
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization United States Citizen

Page 11

CUSIP No. 032724106


1.		Name of Reporting Persons. Nader Naini
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization United States Citizen

Page 12

CUSIP No. 032724106


1.		Name of Reporting Persons. Nathan Every
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization United States Citizen

Page 13

CUSIP No. 032724106


1.		Name of Reporting Persons. Brian Morfitt
2.		Check the Appropriate Box if a Member of a Group (See Instructions) (a) ☐ (b) ☒
3.		SEC USE ONLY
4.		Source of Funds (See Instructions) AF
5.		Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e) ☐
6.		Citizenship or Place of Organization United States Citizen

Page 14

Item 1.

Security and Issuer.

This Amendment No. 4 (Amendment No. 4) to Schedule 13D amends the statement on Schedule 13D filed on February 10, 2017 (the Original Schedule 13D), as amended on February 26, 2018, May 15, 2018 and February 14, 2019 (the Prior Amendments, and together with the Original Schedule 13D and this Amendment No. 3, the Schedule 13D) with respect to the Common Stock of AnaptysBio, Inc. (the Issuer), having its principal executive office at 10421 Pacific Center Court, Suite 200, San Diego, CA 92121. Except as otherwise specified in Amendment No. 4, all items in the Schedule 13D are unchanged. All capitalized terms used in this Amendment No. 4 and not otherwise defined herein have the meanings ascribed to such terms in the Original Schedule 13D.

Item 5.

Interest in Securities of the Issuer

Item 5 of the Original Schedule 13D is hereby amended and restated as follows:

(a)

FH V is the record owner of 0 shares of Common Stock. FM V L.P. is the sole general partner of FH V. FM V L.L.C. is the sole general partner of FM V L.P.

FH VII is the record owner of 700,171 shares of Common Stock (the FH VII Shares) and FH VII-A is the record owner of 199,529 shares of Common Stock (the FH VII-A Shares). As the sole general partner of FH VII and of FH VII-A, FM VII L.P. may be deemed to own beneficially the FH VII Shares and FH VII-A Shares. As the sole general partner of FM VII L.P., FM VII L.L.C. may be deemed to own beneficially the FH VII Shares and FH VII-A Shares. As members of FM VII L.L.C., each of the FM VII Members may be deemed to own beneficially the FH VII Shares and FH VII-A Shares.

As of November 16, 2020, Topper is the record owner of 80,812 shares of Common Stock and 37,083 shares of Common Stock that are issuable upon the exercise of options held directly by Topper that are exercisable within 60 days of November 16, 2020 (collectively, the Topper Shares). Topper is a FM V Member and a FM VII Member and therefore may be deemed to own beneficially the Topper Shares, the FH VII Shares and FH VII-A Shares.

The percentage of outstanding shares of Common Stock of the Issuer, which may be deemed to be beneficially owned by each Reporting Person is set forth on Line 13 of such Reporting Persons cover sheet. Such percentages, other than the percentage for Topper, was calculated based on the 27,347,805 shares of Common Stock outstanding on November 2, 2020 as set forth in the Issuers Form 10-Q filed on November 4, 2020.

Toppers percentage was calculated based on (i) 27,347,805 shares of Common Stock outstanding on November 2, 2020 as set forth in the Issuers Form 10-Q filed on November 4, 2020, and (ii) 37,083 shares of Common Stock that are issuable upon the exercise of options held directly by Topper that are exercisable within 60 days of November 16, 2020.

(b)

Regarding the number of shares as to which such person has:

Sole power to vote or to direct the vote: See line 7 of cover sheets.

Shared power to vote or to direct the vote: See line 8 of cover sheets.

Page 15

Sole power to dispose or to direct the disposition: See line 9 of cover sheets.

Shared power to dispose or to direct the disposition: See line 10 of cover sheets.

(c)

Effective November 16, 2020, FH V, distributed in-kind, without consideration, a total of 973,612 shares of Common Stock of the Issuer to its general and limited partners.

Effective November 16, 2020, FH VII, distributed in-kind, without consideration, a total of 344,860 shares of Common Stock of the Issuer to its general and limited partners.

Effective November 16, 2020, FH VIIA, distributed in-kind, without consideration, a total of 98,275 shares of Common Stock of the Issuer to its general and limited partners.

(d)

No other person is known to have the right to receive or the power to direct the receipt of dividends from, or any proceeds from the sale of, the FH VII Shares, the FH VIIA Shares and the Topper Shares beneficially owned by any of the Reporting Persons, as the case may be.

(e)

November 16, 2020.

Page 16

SIGNATURES

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.


Date: November 18, 2020	FRAZIER HEALTHCARE V, L.P.
	By FHM V, L.P., its general partner
	By FHM V, L.L.C., its general partner

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Date: November 18, 2020	FHM V, L.P.
	By FHM V, L.L.C., its general partner

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Date: November 18, 2020	FHM V, L.L.C.

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Date: November 18, 2020	FRAZIER HEALTHCARE VII, L.P.
	By FHM VII, L.P., its general partner
	By FHM VII, L.L.C., its general partner

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Date: November 18, 2020	FRAZIER HEALTHCARE VII-A, L.P.
	By FHM VII, L.P., its general partner
	By FHM VII, L.L.C., its general partner

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Page 17


Date: November 18, 2020	FHM VII, L.P.
	By FHM VII, L.L.C., its general partner

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Date: November 18, 2020	FHM VII, L.L.C.

	By:	/s/ Steve R. Bailey
		Steve R. Bailey, Chief Financial Officer

Date: November 18, 2020	By:	*
		James Topper

Date: November 18, 2020	By:	*
		Patrick Heron

Date: November 18, 2020	By:	*
		Nader Naini

Date: November 18, 2020	By:	*
		Nathan Every

Date: November 18, 2020	By:	*
		Brian Morfitt

Date: November 18, 2020	By:	*
		Alan Frazier

Date: November 18, 2020	*By:	/s/ Steve R. Bailey
		Steve R. Bailey, as Attorney-in-Fact

This Schedule 13D was executed by Steve R. Bailey on behalf of the individuals listed above pursuant to a Power of Attorney, a copy of which was filed with the SEC on May 15, 2018.

Page 18