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NUMBER OF

UNITS

BENEFICIALLY

OWNED BY

EACH

REPORTING

PERSON

WITH

SOLE VOTING POWER

-0-

SHARED VOTING POWER

777,411 (1)

SOLE DISPOSITIVE POWER

-0-

SHARED DISPOSITIVE POWER

777,411 (1)

Accession Number:: 0001193125-19-302571
Form Type:: 13D Filing
Publication Date:: 2019-11-27 16:17:59

Filed By:: Sibling Capital Ventures Llc
Company:: Tricida Inc.
Filing Date:: 2019-11-27
SEC Url:: 13D Filing

Ownership Summary

Please notice the below summary table is generated without human intervention and may contain errors. Please refer to the complete filing displayed below for exact figures.

Name	Sole Voting Power	Shared Voting Power	Sole Dispositive Power	Shared Dispositive Power	Aggregate Amount Owned Power	Percent of Class
SIBLING CAPITAL VENTURES	0	777,411	0	777,411	777,411	1.6%
SIBLING CAPITAL VENTURES II	0	2,773,350	0	2,773,350	2,773,350	5.6%
SIBLING CAPITAL VENTURES III	0	1,810,195	0	1,810,195	1,810,195	3.6%
SIBLING CAPITAL VENTURES IV	0	599,379	0	599,379	599,379	1.2%
SIBLING CAPITAL FUND II-A	777,411	0	777,411	0	777,411	1.6%
SIBLING CAPITAL FUND II-B	2,773,350	0	2,773,350	0	2,773,350	5.6%
SIBLING CAPITAL FUND II-C	1,810,195	0	1,810,195	0	1,810,195	3.6%
SIBLING CAPITAL FUND II-D	599,379	0	599,379	0	599,379	1.2%
SIBLING INSIDERS II	0	463,158	0	463,158	463,158	0.9%
SIBLING INSIDERS FUND II	463,158	0	463,158	0	463,158	0.9%
BRIAN M. ISERN	0	6,423,493	0	6,423,493	6,423,493	12.9%
SANDRA I. COUFAL, M.D	234,221	6,429,973	234,221	6,429,973	6,664,194	13.4%

Filing

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13D

Under the Securities Exchange Act of 1934

(Amendment No. 2)

Tricida, Inc.

(Name of Issuer)

Common Stock, par value $0.001 per share

(Title of Class of Securities)

89610F101

(CUSIP Number)

Sibling Capital Ventures LLC

c/o Brian Isern

500 Yale Avenue North

Seattle, WA 98109

Tel: (504) 715-8335

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)

November 22, 2019

(Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of Rule 13d-1(e), Rule 13d-1(f) or Rule 13d-1(g), check the following box. ☐

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

*	The remainder of this cover page shall be filled out for a reporting persons initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed to be filed for the purpose of Section 18 of the Securities Exchange Act of 1934 (Act) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL VENTURES LLC
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Sibling Capital Fund II-A L.P. is a direct beneficial owner of 777,411 shares of Common Stock. As the sole general partner of Sibling Capital Fund II-A L.P., Sibling Capital Ventures LLC may be deemed to have shared voting and/or dispositive power with respect to such shares.

(2)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL VENTURES II LLC
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Sibling Capital Fund II-B L.P. is a direct beneficial owner of 2,773,350 shares of Common Stock. As the sole general partner of Sibling Capital Fund II-B L.P., Sibling Capital Ventures II LLC may be deemed to have shared voting and/or dispositive power with respect to such shares.

(2)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL VENTURES III LLC
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Sibling Capital Fund II-C L.P. is a direct beneficial owner of 1,810,195 shares of Common Stock. As the sole general partner of Sibling Capital Fund II-C L.P., Sibling Capital Ventures III LLC may be deemed to have shared voting and/or dispositive power with respect to such shares.

(2)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL VENTURES IV LLC
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Sibling Capital Fund II-D L.P. is a direct beneficial owner of 599,379 shares of Common Stock. As the sole general partner of Sibling Capital Fund II-D L.P., Sibling Capital Ventures IV LLC may be deemed to have shared voting and/or dispositive power with respect to such shares.

(2)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL FUND II-A L.P.
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS WC
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL FUND II-B L.P.
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS WC
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL FUND II-C L.P.
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS WC
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING CAPITAL FUND II-D L.P.
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS WC
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING INSIDERS II LLC
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Sibling Insiders Fund II L.P. is a direct beneficial owner of 463,158 shares of Common Stock. As the sole general partner of Sibling Insiders Fund II L.P., Sibling Insiders II LLC may be deemed to have shared voting and/or dispositive power with respect to such shares.

(2)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SIBLING INSIDERS FUND II L.P.
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS WC
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION DELAWARE, UNITED STATES

(1)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS BRIAN M. ISERN
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION UNITED STATES

(1)

As co-manager of Sibling Capital Ventures LLC, Sibling Capital Ventures II LLC, Sibling Capital Ventures III LLC, Sibling Capital Ventures IV LLC and Sibling Insiders II LLC, Brian M. Isern may be deemed to have shared voting and/or dispositive power with respect to shares held by Sibling Capital Fund II-A L.P., Sibling Capital Fund II-B L.P., Sibling Capital Fund II-C L.P., Sibling Capital Fund II-D L.P. and Sibling Insiders Fund II L.P.

(2)	Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

CUSIP No. 89610F101


1		NAME OF REPORTING PERSONS SANDRA I. COUFAL, M.D.
2		CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ☐ (b) ☒
3		SEC USE ONLY
4		SOURCE OF FUNDS AF, PF
5		CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEM 2(d) OR 2(e) ☐
6		CITIZENSHIP OR PLACE OF ORGANIZATION UNITED STATES

(1)	Includes (a) 18,448 shares of Common Stock Sandra I. Coufal has a right to acquire pursuant to options within 60 days of the date hereof and (b) 3,632 shares of Common Stock Sandra I. Coufal has a right to acquire pursuant to restricted stock units within 60 days of the date hereof.

(2)

As co-manager of Sibling Capital Ventures LLC, Sibling Capital Ventures II LLC, Sibling Capital Ventures III LLC, Sibling Capital Ventures IV LLC and Sibling Insiders II LLC, Sandra. I Coufal may be deemed to have shared voting and/or dispositive power with respect to shares held by Sibling Capital Fund II-A L.P., Sibling Capital Fund II-B L.P., Sibling Capital Fund II-C L.P., Sibling Capital Fund II-D L.P. and Sibling Insiders Fund II L.P.

(3)	Includes 6,480 shares of Common Stock owned by the Coufal Irrevocable Trust, of which Sandra I. Coufals spouse is the trustee.

(4)

Based on 49,635,410 shares of Common Stock, calculated as follows: (a) 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019, plus (b) 18,448 shares of Common Stock Sandra I. Coufal has a right to acquire pursuant to options within 60 days of the date hereof, plus (c) 3,632 shares of Common Stock Sandra I. Coufal has a right to acquire pursuant to restricted stock units within 60 days of the date hereof.

Item 1.

SECURITY AND ISSUER

The name of the issuer is Tricida, Inc., a Delaware corporation (the Issuer). The address of the Issuers principal executive offices is 7000 Shoreline Court, Suite 201, South San Francisco, CA 94080. This Amendment No. 2 (this Amendment No. 2) to the Schedule 13D filed on July 12, 2018 (the Statement) relates to the Issuers Common Stock, par value $0.001 per share (the Common Stock).

Item 2.

IDENTITY AND BACKGROUND

(a)

This Amendment No. 2 is being filed jointly by:

(i)

Sibling Capital Ventures LLC, a Delaware limited liability company (SCV)

(ii)

Sibling Capital Ventures II LLC, a Delaware limited liability company (SCV II)

(iii)

Sibling Capital Ventures III LLC, a Delaware limited liability company (SCV III)

(iv)

Sibling Capital Ventures IV LLC, a Delaware limited liability company (SCV IV)

(v)

Sibling Capital Fund II-A L.P., a Delaware limited partnership (Sibling A)

(vi)

Sibling Capital Fund II-B L.P., a Delaware limited partnership (Sibling B)

(vii)

Sibling Capital Fund II-C L.P., a Delaware limited partnership (Sibling C)

(viii)

Sibling Capital Fund II-D L.P., a Delaware limited partnership (Sibling D)

(ix)

Sibling Insiders II LLC, a Delaware limited liability company (Sibling Insiders LLC)

(x)

Sibling Insiders Fund II L.P., a Delaware limited partnership (Sibling Insiders Fund)

(xi)

Brian M. Isern, a United States citizen (Mr. Isern)

(xii)

Sandra I. Coufal, M.D., a United States citizen (Dr. Coufal)

SCV, SCV II, SCV III, SCV IV, Sibling A, Sibling B, Sibling C, Sibling D, Sibling Insiders LLC, Sibling Insiders Fund, Mr. Isern and Dr. Coufal are referred to herein collectively as the Reporting Persons and individually as a Reporting Person.

The Reporting Persons may be deemed part of a group within the meaning of Section 13(d) of the Act. Accordingly, such group may be deemed to collectively beneficially own 6,664,194 shares of Common Stock, representing approximately 13.4% of the Common Stock outstanding as of November 22, 2019. The filing of this Amendment No. 2 shall not be construed as an admission that the Reporting Persons are part of a group within the meaning of Section 13(d) of the Act.

(b)

The principal business address of each of SCV, SCV II, SCV III, SCV IV, Sibling A, Sibling B, Sibling C, Sibling D, Sibling Insiders LLC, Sibling Insiders Fund and Mr. Isern is 500 Yale Avenue North, Seattle, WA 98109. The principal business address of Dr. Coufal is 18313 Calle La Serra, Rancho Santa Fe, CA 92091.

(c)

(i)

The principal business of SCV is to serve as the sole general partner of Sibling A.

(ii)

The principal business of SCV II is to serve as the sole general partner of Sibling B.

(iii)

The principal business of SCV III is to serve as the sole general partner of Sibling C.

(iv)

The principal business of SCV IV is to serve as the sole general partner of Sibling D.

(v)

The principal business of Sibling A is to invest in securities.

(vi)

The principal business of Sibling B is to invest in securities.

(vii)

The principal business of Sibling C is to invest in securities.

(viii)

The principal business of Sibling D is to invest in securities.

(ix)

The principal business of Sibling Insiders LLC is to serve as the sole general partner of Sibling Insiders Fund.

(x)

The principal business of Sibling Insiders Fund is to invest in securities.

(xi)

The principal occupation of Mr. Isern is to serve as a co-manager of each of SCV, SCV II, SCV III, SCV IV and Sibling Insiders LLC.

(xii)

The principal occupation of Dr. Coufal is to serve as a biomedical consultant for Sandra I. Coufal, M.D., Inc., the principal address of which is 18313 Calle La Serra, Rancho Santa Fe, CA 92091. Dr. Coufal also serves as the co-manager of each of SCV, SCV II, SCV III, SCV IV and Sibling Insiders LLC and a director of the Issuer.

(d)

None of the Reporting Persons have, during the last five years, been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors). To the best of the Reporting Persons knowledge, none of their respective executive officers or directors, as applicable, have, during the last five years, been convicted in a criminal proceeding (excluding traffic violations or similar misdemeanors).

(e)

None of the Reporting Persons have, during the last five years, been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws. To the best of the Reporting Persons knowledge, none of their respective executive officers or directors, as applicable, have, during the last five years, been a party to a civil proceeding of a judicial or administrative body of competent jurisdiction and as a result of such proceeding was or is subject to a judgment, decree or final order enjoining future violations of, or prohibiting or mandating activities subject to, federal or state securities laws or finding any violation with respect to such laws.

(f)

The information set forth in Item 2(a) of this Amendment No. 2 is incorporated herein by reference.

Item 3.

SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION

The Reporting Persons acquired certain ownership interests in the Issuer prior to the Issuers initial public offering that closed on July 2, 2018 in the following transactions:

(i)

On August 5, 2013, Dr. Coufal acquired 950,000 shares of Common Stock for an aggregate purchase price of $950.00. Dr. Coufal financed the purchased with her personal funds. On August 27, 2017, Dr. Coufal transferred 100,000 of such shares to the Coufal Irrevocable Trust.

(ii)

On December 18, 2013, Sibling A acquired 3,555,304 shares of Series A Convertible Preferred Stock for an aggregate purchase price of $3,149,999.34. Sibling A financed the purchase with funds from its working capital.

(iii)

On February 13, 2015, Sibling B acquired 7,080,847 shares of Series B Convertible Preferred Stock for an aggregate purchase price of $6,585,187.71. Sibling B financed the purchase with funds from its working capital.

(iv)

On February 2, 2016, Sibling B acquired 5,414,765 shares of Series B Convertible Preferred Stock for an aggregate purchase price of $5,035,731.45. Sibling B financed the purchase with funds from its working capital.

(v)

On August 4, 2016, Sibling C acquired 3,929,770 shares of Series C Convertible Preferred Stock for an aggregate purchase price of $6,091,143.50. Sibling C financed the purchase with funds from its working capital.

(vi)

On April 25, 2017, Sibling C acquired 3,274,808 shares of Series C Convertible Preferred Stock for an aggregate purchase price of $5,075,952.40. Sibling C financed the purchase with funds from its working capital.

(vii)

On November 7, 2017, Sibling D acquired 2,385,532 shares of Series D Convertible Preferred Stock for an aggregate purchase price of $5,606,000.20. Sibling D financed the purchase with funds from its working capital.

On June 15, 2018, the Issuer effected a 1-for-3.98 reverse stock split of its outstanding Common Stock, including the shares held by the Reporting Persons as listed in paragraph (i) above.

Upon the completion of the Issuers initial public offering on July 2, 2018, all the Issuers outstanding shares of convertible preferred stock were converted into shares of Common Stock at a rate of 1/3.98 (or on an approximately 1-for-0.251256 basis).

Additionally, the Reporting Persons acquired certain ownership interests in the Issuer in connection with the Issuers initial public offering in the following transactions:

(i)

On July 2, 2018, Dr. Coufal acquired an option to purchase 13,147 shares of Common Stock as equity compensation for her services as a director of the Issuer. Dr. Coufal has a right to acquire 13,147 shares of Common Stock pursuant to the option within 60 days of the date hereof.

(ii)

On July 2, 2018, Dr. Coufal acquired 3,632 restricted stock units as equity compensation for her services as a director of the Issuer. Each restricted stock unit represents a contingent right to receive one share of Common Stock. Dr. Coufal has a right to acquire 3,632 shares of Common Stock pursuant to the restricted stock units within sixty days of the date hereof.

(iii)

On July 2, 2018, Sibling Insiders Fund acquired 463,158 shares of Common Stock for an aggregate purchase price of $8,800,002.00. Sibling Insiders Fund financed the purchase with funds from its working capital.

Further, the Reporting Persons acquired certain ownership interests in the Issuer following the Issuers initial public offering in the following transactions:

(i)

On March 31, 2019, Dr. Coufal acquired an option to purchase 7,068 shares of Common Stock as equity compensation for her services as a director of the Issuer. Subject to certain conditions, the option is scheduled to vest ratably on a monthly basis, on the monthly anniversary of March 31, 2019 (the Option Date), over the one-year period following the Option Date so that the option shall be 100% vested and exercisable on the one-year anniversary of the Option Date. Dr. Coufal has a right to acquire 5,301 shares of Common Stock pursuant to the option within 60 days of the date hereof.

(ii)

On March 31, 2019, Dr. Coufal acquired 1,879 restricted stock units as equity compensation for her services as a director of the Issuer. Each restricted stock unit represents a contingent right to receive one share of Common Stock. Subject to certain conditions, the restricted stock units are scheduled to vest on the earlier of (i) the one-year anniversary of March 31, 2019 (the Grant Date) and (ii) the Issuers next regularly scheduled annual meeting of the stockholders that occurs following the Grant Date. Dr. Coufal does not have a right to acquire any shares of Common Stock pursuant to the restricted stock units within sixty days of the date hereof.

Item 4.

PURPOSE OF TRANSACTION

As a result of certain transactions by the Reporting Persons, the percentage of outstanding shares of Common Stock that the Reporting Persons may be deemed to beneficially own was reduced by more than one percent since the filing of Amendment No. 1 to the Statement on April 11, 2019.

The securities covered by this Amendment No. 2 were acquired for investment purposes.

Dr. Coufal has served on the board of directors of the Issuer since July 2013. As a director of the Issuer, Dr. Coufal may have influence over the corporate activities of the Issuer, including activities which may relate to the transactions described in subparagraphs (a) through (j) of Item 4 of Schedule 13D.

Except as set forth above, the Reporting Persons have no present plans or proposals that relate to, or that would result in, any of the actions described in subparagraphs (a) through (j) of Item 4 of Schedule 13D; however, as part of their ongoing evaluation of the investment described in this Amendment No. 2 and investment alternatives, the Reporting Persons may consider such matters in the future, and subject to applicable law, may formulate a plan with respect to such matters, and, from time to time, the Reporting Persons may hold discussions with management or the board of directors of the Issuer, other holders of securities of the Issuer or other third parties regarding such matters. The Reporting Persons retain the right to change their investment intent, and may, from time to time, acquire additional shares of Common Stock or other securities of the Issuer, or sell or otherwise dispose of (or enter into plans or arrangements to sell or otherwise dispose of), all or part of the shares of Common Stock or other securities of the Issuer, if any, beneficially owned by them, in any manner permitted by law.

Item 5.

INTEREST IN SECURITIES OF THE ISSUER

(a) - (b)

The aggregate number and percentage of Common Stock beneficially owned by the Reporting Persons are as follows:


Sibling Capital Ventures LLC
Amount beneficially owned:	777,411	(1)
Percent of class:	1.6	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	0
Shared power to vote or direct the vote:	777,411	(1)
Sole power to dispose or direct the disposition of:	0
Shared power to dispose or direct the disposition of:	777,411	(1)
Sibling Capital Ventures II LLC
Amount beneficially owned:	2,773,350	(2)
Percent of class:	5.6	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	0
Shared power to vote or direct the vote:	2,773,350	(2)
Sole power to dispose or direct the disposition of:	0
Shared power to dispose or direct the disposition of:	2,773,350	(2)
Sibling Capital Ventures III LLC
Amount beneficially owned:	1,810,195	(3)
Percent of class:	3.6	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	0
Shared power to vote or direct the vote:	1,810,195	(3)
Sole power to dispose or direct the disposition of:	0
Shared power to dispose or direct the disposition of:	1,810,195	(3)


Sibling Capital Ventures IV LLC
Amount beneficially owned:	599,379	(4)
Percent of class:	1.2	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	0
Shared power to vote or direct the vote:	599,379	(4)
Sole power to dispose or direct the disposition of:	0
Shared power to dispose or direct the disposition of:	599,379	(4)
Sibling Capital Fund II-A L.P.
Amount beneficially owned:	777,411
Percent of class:	1.6	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	777,411
Shared power to vote or direct the vote:	0
Sole power to dispose or direct the disposition of:	777,411
Shared power to dispose or direct the disposition of:	0
Sibling Capital Fund II-B L.P.
Amount beneficially owned:	2,773,350
Percent of class:	5.6	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	2,773,350
Shared power to vote or direct the vote:	0
Sole power to dispose or direct the disposition of:	2,773,350
Shared power to dispose or direct the disposition of:	0
Sibling Capital Fund II-C L.P.
Amount beneficially owned:	1,810,195
Percent of class:	3.6	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	1,810,195
Shared power to vote or direct the vote:	0
Sole power to dispose or direct the disposition of:	1,810,195
Shared power to dispose or direct the disposition of:	0
Sibling Capital Fund II-D L.P.
Amount beneficially owned:	599,379
Percent of class:	1.2	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	599,379
Shared power to vote or direct the vote:	0
Sole power to dispose or direct the disposition of:	599,379
Shared power to dispose or direct the disposition of:	0
Sibling Insiders II LLC
Amount beneficially owned:	463,158	(5)
Percent of class:	0.9	% (10)
Number of shares as to which the person has:


Sole power to vote or direct the vote:	0
Shared power to vote or direct the vote:	463,158	(5)
Sole power to dispose or direct the disposition of:	0
Shared power to dispose or direct the disposition of:	463,158	(5)
Sibling Insiders Fund II L.P.
Amount beneficially owned:	463,158
Percent of class:	0.9	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	463,158
Shared power to vote or direct the vote:	0
Sole power to dispose or direct the disposition of:	463,158
Shared power to dispose or direct the disposition of:	0
Brian M. Isern
Amount beneficially owned:	6,423,493	(6)
Percent of class:	12.9	% (10)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	0
Shared power to vote or direct the vote:	6,423,493	(6)
Sole power to dispose or direct the disposition of:	0
Shared power to dispose or direct the disposition of:	6,423,493	(6)
Sandra I. Coufal, M.D.
Amount beneficially owned:	6,664,194	(7) (8) (9)
Percent of class:	13.4	% (11)
Number of shares as to which the person has:
Sole power to vote or direct the vote:	234,221	(9)
Shared power to vote or direct the vote:	6,429,973	(7) (8)
Sole power to dispose or direct the disposition of:	234,221	(9)
Shared power to dispose or direct the disposition of:	6,429,973	(7) (8)

(1)

Sibling A is a direct beneficial owner of 777,411 shares of Common Stock. As the sole general partner of Sibling A, SCV may be deemed to have shared voting and/or dispositive power with respect to such shares.

(2)

Sibling B is a direct beneficial owner of 2,773,350 shares of Common Stock. As the sole general partner of Sibling B, SCV II may be deemed to have shared voting and/or dispositive power with respect to such shares.

(3)

Sibling C is a direct beneficial owner of 1,810,195 shares of Common Stock. As the sole general partner of Sibling C, SCV III may be deemed to have shared voting and/or dispositive power with respect to such shares.

(4)

Sibling D is a direct beneficial owner of 599,379 shares of Common Stock. As the sole general partner of Sibling D, SCV IV may be deemed to have shared voting and/or dispositive power with respect to such shares.

(5)

Sibling Insiders Fund is a direct beneficial owner of 463,158 shares of Common Stock. As the sole general partner of Sibling Insiders Fund, Sibling Insiders LLC may be deemed to have shared voting and/or dispositive power with respect to such shares.

(6)

As co-manager of SCV, SCV II, SCV III, SCV IV and Sibling Insiders LLC, Mr. Isern may be deemed to have shared voting and/or dispositive power with respect to shares held by Sibling A, Sibling B, Sibling C, Sibling D and Sibling Insiders Fund.

(7)

As co-manager of SCV, SCV II, SCV III, SCV IV and Sibling Insiders LLC, Dr. Coufal may be deemed to have shared voting and/or dispositive power with respect to shares held by Sibling A, Sibling B, Sibling C, Sibling D and Sibling Insiders Fund.

(8)

Includes 6,480 shares of Common Stock owned by the Coufal Irrevocable Trust, of which Dr. Coufals spouse is the trustee.

(9)

Includes (a) 18,448 shares of Common Stock Dr. Coufal has a right to acquire pursuant to options within 60 days of the date hereof and (b) 3,632 shares of Common Stock Dr. Coufal has a right to acquire pursuant to restricted stock units within 60 days of the date hereof.

(10)

Based on 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019.

(11)

Based on 49,635,410 shares of Common Stock, calculated as follows: (a) 49,613,330 shares of Common Stock outstanding as of November 7, 2019, as reported in the Issuers Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 14, 2019, plus (b) 18,448 shares of Common Stock the Reporting Person has a right to acquire pursuant to options within 60 days of the date hereof, plus (c) 3,632 shares of Common Stock the Reporting Person has a right to acquire pursuant to restricted stock units within 60 days of the date hereof.

(c)

Annex A hereof sets forth the transactions by the Reporting Persons in the securities of the Issuer from the 60 days prior to the date of the event which requires the filing of this Amendment No. 2 up through the date hereof. Except as otherwise disclosed in Annex A, none of the Reporting Persons, nor, to the best of the Reporting Persons knowledge, any of their respective executive officers or directors, as applicable, has acquired or disposed of, any securities of the Issuer from the 60 days prior to the date of the event which requires the filing of this Amendment No. 2 up through the date hereof.

(d)

Except as set forth herein, no other person is known by the Reporting Persons to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, Common Stock beneficially owned by the Reporting Persons.

(e)

Not applicable.

Item 6.

CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH RESPECT TO SECURITIES OF THE ISSUER

Pursuant to Rule 13d-1(k) promulgated under the Act, the Reporting Persons entered into a Joint Filing Agreement (the Joint Filing Agreement) with respect to the joint filing of the Statement and any amendment or amendments thereto. The foregoing description of the Joint Filing Agreement does not purport to be complete and is qualified in its entirety by the contents of the Joint Filing Agreement, a copy of which is attached hereto as Exhibit A and is incorporated herein by reference.

Pursuant to an amended and restated investor rights agreement with the Issuer (as amended, the Investor Rights Agreement), Sibling A, Sibling B, Sibling C and Sibling D are entitled to certain rights with respect to the registration of the offer and sale of shares of Common Stock they hold. The registration rights include the right to demand that the Issuer file a registration statement or request that their shares be covered by a registration statement that the Issuer is otherwise filing, subject, in each case, to certain exceptions. If the offer and sale of these shares are registered, they will be freely tradable without restriction under the Securities Act. The foregoing description of the Investor Rights Agreement does not purport to be complete and is qualified in its entirety by the contents of the Investor Rights Agreement, a copy of which is attached hereto as Exhibit B and is incorporated herein by reference.

As a director of the Issuer, Dr. Coufal participates in the equity incentive plans the Issuer may have from time to time, including the Issuers 2018 Equity Incentive Plan, a copy of which is attached hereto as Exhibit C and is incorporated herein by reference. Dr. Coufal has entered into award agreements under the Issuers 2018 Equity Incentive Plan (i) substantially in the form of the Issuers Director Restricted Stock Unit Award Agreement, a copy of which is attached hereto as Exhibit D and is incorporated herein by reference, and (ii) substantially in the form of the Issuers Director Stock Option Agreement, a copy of which is attached hereto as Exhibit E and is incorporated herein by reference.

Except as described in this Item 6, there are no contracts, arrangements, understandings or relationships (legal or otherwise) between the persons named in Item 2 or, to the best of the Reporting Persons knowledge, between such persons and any other person with respect to any securities of the Issuer, including, but not limited to, transfer or voting of any of the securities, finders fees, joint ventures, loan or option arrangements, puts or calls, guarantees of profits, division of profits or loss, or the giving or withholding of proxies, including any securities pledged or otherwise subject to a contingency the occurrence of which would give another person voting power or investment power over such securities other than standard default and similar provisions contained in loan agreements.

Item 7.

MATERIAL TO BE FILED AS EXHIBITS


Exhibit A:		Joint Filing Agreement (incorporated herein by reference to Exhibit A to the Reporting Persons Schedule 13D, filed with the Securities and Exchange Commission on July 12, 2018)

Exhibit B:		Investor Rights Agreement (incorporated herein by reference to Exhibits 4.1 and 4.2 to the Issuers Registration Statement on Form S-1, filed with the Securities and Exchange Commission on June 4, 2018)

Exhibit C:		Issuers 2018 Equity Incentive Plan (incorporated herein by reference to Exhibit 10.3 to the Issuers Amendment No. 2 to Form S-1, filed with the Securities and Exchange Commission on June 25, 2018)

Exhibit D:		Issuers Director Restricted Stock Unit Award Agreement (incorporated herein by reference to Exhibit 10.4 to the Issuers Amendment No. 2 to Form S-1, filed with the Securities and Exchange Commission on June 25, 2018)

Exhibit E:		Issuers Director Stock Option Agreement (incorporated herein by reference to Exhibit 10.5 to the Issuers Amendment No. 2 to Form S-1, filed with the Securities and Exchange Commission on June 25, 2018)

SIGNATURES

After reasonable inquiry and to the best of his or its knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct.

Date: November 27, 2019


SIBLING CAPITAL VENTURES LLC

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING CAPITAL VENTURES II LLC

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING CAPITAL VENTURES III LLC

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING CAPITAL VENTURES IV LLC

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

/s/ Brian M. Isern
Brian M. Isern, in his individual capacity

/s/ Sandra I. Coufal
Sandra I. Coufal, M.D., in her individual capacity

SIBLING CAPITAL FUND II-A L.P.

By:		Sibling Capital Ventures LLC, its general partner

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING CAPITAL FUND II-B L.P.

By: Sibling Capital Ventures II LLC, its general partner

By:		/s/ Brian M. Isern
		Brian M. Isern
		President


SIBLING CAPITAL FUND II-C L.P.

By: Sibling Capital Ventures III LLC, its general partner

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING CAPITAL FUND II-D L.P.

By: Sibling Capital Ventures IV LLC, its general partner

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING INSIDERS II LLC

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

SIBLING INSIDERS FUND II L.P.

By: Sibling Insiders II LLC, its general partner

By:		/s/ Brian M. Isern
		Brian M. Isern
		President

Annex A

Schedule of Transactions

Reporting Person

Date of Transaction

Security

Amount of Securities
Bought (Sold)

Unit Cost

Transaction Type

Dr. Coufal

11/01/2019

Common Stock

(713

)

(1)

Open Market Sale

Dr. Coufal

11/20/2019

Common Stock

(713

)

(2)

Open Market Sale

Sibling A

11/20/2019

Common Stock

(19,173

)

(3)

Open Market Sale

Sibling A

11/20/2019

Common Stock

(37,614

)

(4)

Open Market Sale

Sibling B

11/20/2019

Common Stock

(20,222

)

(5)

Open Market Sale

Sibling B

11/20/2019

Common Stock

(33,576

)

(6)

Open Market Sale

Sibling A

11/21/2019

Common Stock

(59,094

)

(7)

Open Market Sale

Sibling B

11/21/2019

Common Stock

(13,648

)

(8)

Open Market Sale

Sibling B

11/21/2019

Common Stock

(117,940

)

(9)

Open Market Sale

Sibling B

11/22/2019

Common Stock

(48,030

)

(10)

Open Market Sale

Sibling B

11/22/2019

Common Stock

(132,834

)

(11)

Open Market Sale

(1)	Dr. Coufal sold 713 shares of Common Stock at an average price of $38.86 per share. These shares were sold in multiple transactions at prices ranging from $38.73 to $38.99, inclusive.

(2)	Dr. Coufal sold 713 shares of Common Stock at an average price of $40.21 per share. These shares were sold in multiple transactions at prices ranging from $40.03 to $40.48, inclusive.

(3)	Sibling A sold 19,173 shares of Common Stock at an average price of $39.54 per share. These shares were sold in multiple transactions at prices ranging from $39.40 to $40.00, inclusive.

(4)	Sibling A sold 37,614 shares of Common Stock at an average price of $40.27 per share. These shares were sold in multiple transactions at prices ranging from $40.01 to $40.88, inclusive.

(5)	Sibling B sold 20,222 shares of Common Stock at an average price of $39.55 per share. These shares were sold in multiple transactions at prices ranging from $39.38 to $40.00, inclusive.

(6)	Sibling B sold 33,576 shares of Common Stock at an average price of $40.19 per share. These shares were sold in multiple transactions at prices ranging from $40.01 to $40.75, inclusive.

(7)	Sibling A sold 59,094 shares of Common Stock at an average price of $41.09 per share. These shares were sold in multiple transactions at prices ranging from $40.53 to $41.33, inclusive.

(8)	Sibling B sold 13,648 shares of Common Stock at an average price of $40.31 per share. These shares were sold in multiple transactions at prices ranging from $39.86 to $40.50, inclusive.

(9)	Sibling B sold 117,940 shares of Common Stock at an average price of $41.01 per share. These shares were sold in multiple transactions at prices ranging from $40.51 to $41.35, inclusive.

(10)	Sibling B sold 48,030 shares of Common Stock at an average price of $40.53 per share. These shares were sold in multiple transactions at prices ranging from $40.01 to $40.89, inclusive.

(11)	Sibling B sold 132,834 shares of Common Stock at an average price of $41.17 per share. These shares were sold in multiple transactions at prices ranging from $40.90 to $41.61, inclusive.