Filing Details

 

 

 

 

 

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act, but shall be subject to all other provisions of the Act (however, see the Notes).

Sienna Biopharmaceuticals, Inc. (the "Issuer").

 

30699 Russell Ranch Road, Suite 140, Westlake Village, CA  91362

 

ARCH Venture Fund VIII, L.P. ("ARCH Venture Fund VIII"); ARCH Venture Fund VIII Overage, L.P. ("AVF VIII Overage LP"); ARCH Venture Partners VIII, L.P. ("AVP VIII LP"); ARCH Venture Partners VIII, LLC ("AVP VIII LLC") (collectively, the "Reporting Entities" and individually, each a "Reporting Entity"); and Keith Crandell ("Crandell"), Robert Nelsen ("Nelsen") and Clinton Bybee ("Bybee") (collectively, the "Managing Directors" and individually, each a "Managing Director").  The Reporting Entities and the Managing Directors collectively are referred to as the "Reporting Persons".

 

8755 W. Higgins Avenue, Suite 1025, Chicago, IL 60631

 

ARCH Venture Fund VIII, AVF VIII Overage LP and AVP VIII LP are limited partnerships organized under the laws of the State of Delaware. AVP VIII LLC is a limited liability company organized under the laws of the State of Delaware.  Each Managing Director is a US citizen.

 

 

82622H108

 

Not Applicable.

 

(a)

Amount beneficially owned:

(b)

Percent of class:

 

See line 2 of the cover sheets. The percentages set forth on the cover sheet for each Reporting Person (other than Nelsen) is based upon 21,140,101 shares of common stock outstanding as of November 5, 2018 as reported on the Issuers Form 10-Q as filed with the Securities and Exchange Commission on November 8, 2018.

See line 5 of the cover sheets.

 

See line 6 of the cover sheets.

 

    See line 7 of the cover sheets.

 

    See line 8 of the cover sheets.

 

 

Item 10.

Certification

 

 

 

 

	ARCH VENTURE PARTNERS VIII, L.P.
	By:   ARCH Venture Partners VIII, LLC
	its General Partner

 

	*
	Keith Crandell

This Amendment No. 1 to Schedule 13G was executed by Mark McDonnell pursuant to Powers of Attorney attached hereto as Exhibit 2.0 and Exhibit 2.1 and incorporated herein by reference.

 

 

 

 

 

 

	ARCH VENTURE PARTNERS VIII, L.P.
	By:   ARCH Venture Partners VIII, LLC
	its General Partner

 

	*
	Keith Crandell

 

This Agreement was executed by Mark McDonnell pursuant to Powers of Attorney attached hereto as Exhibit 2.0 and Exhibit 2.1 and incorporated herein by reference.

 

KNOW ALL MEN BY THESE PRESENTS, that each person whose signature appears below hereby constitutes and appoints Mark McDonnell his true and lawful attorney-in-fact, with full power of substitution, to sign any and all instruments, certificates and documents that may be necessary, desirable or appropriate to be executed on behalf of himself as an individual or in his capacity as a direct or indirect general partner, member, director, officer or manager of any partnership, corporation or limited liability company, pursuant to section 13 or 16 of the Securities Exchange Act of 1934, as amended (the "Exchange Act"), and any and all regulations promulgated thereunder, and to file the same, with all exhibits thereto, and any other documents in connection therewith, with the Securities and Exchange Commission, and with any other entity when and if such is mandated by the Exchange Act or by the Financial Industry Regulatory Authority, granting unto said attorney-in-fact full power and authority to do and perform each and every act and thing necessary, desirable or appropriate, fully to all intents and purposes as he might or could do in person, thereby ratifying and confirming all that said attorney-in-fact, or his substitutes, may lawfully do or cause to be done by virtue hereof. This Power of Attorney shall remain in full force and effect with respect to each undersigned person unless and until six months after such person is both no longer a Managing Director of ARCH Venture Partners and no longer serving on the board of directors of any portfolio company of any ARCH Venture Partners fund.

IN WITNESS WHEREOF, this Power of Attorney has been signed as of the 9^th day of March, 2015.

 

 

 

 

 

	ARCH VENTURE PARTNERS VIII, L.P.
	By:   ARCH Venture Partners VIII, LLC
	its General Partner

 

	/s/ Keith Crandell
	Keith Crandell

 

	By:   /s/ Keith Crandell
	Managing Director

 

 

	ARCH VENTURE PARTNERS VIII, L.P.
	By:   ARCH Venture Partners VIII, LLC
	its General Partner