Filing Details

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

x

Rule 13d-1(b)

o

Rule 13d-1(c)

o

Rule 13d-1(d)

CUSIP No. 503459604

1.

Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).

Sectoral Asset Management Inc.

2.

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

o

(b)

o

3.

SEC Use Only

4.

Citizenship or Place of Organization:
Canada

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

5.

Sole Voting Power
1,084,227

6.

Shared Voting Power
-0-

7.

Sole Dispositive Power
1,759,171

8.

Shared Dispositive Power
-0-

9.

Aggregate Amount Beneficially Owned by Each Reporting Person
1,759,171

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions). o

11.

Percent of Class Represented by Amount in Row (9)
6.7%

12.

Type of Reporting Person (See Instructions)
IA

CUSIP No. 503459604

1.

Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).

Jérôme G. Pfund

2.

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

o

(b)

o

3.

SEC Use Only

4.

Citizenship or Place of Organization:
Swiss

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

5.

Sole Voting Power
1,084,227

6.

Shared Voting Power
-0-

7.

Sole Dispositive Power
1,759,171

8.

Shared Dispositive Power
-0-

9.

Aggregate Amount Beneficially Owned by Each Reporting Person
1,759,171

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions). o

11.

Percent of Class Represented by Amount in Row (9)
6.7%

12.

Type of Reporting Person (See Instructions)
IN

CUSIP No. 503459604

1.

Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).

Michael L. Sjöström

2.

Check the Appropriate Box if a Member of a Group (See Instructions)

(a)

o

(b)

o

3.

SEC Use Only

4.

Citizenship or Place of Organization:
Swiss

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

5.

Sole Voting Power
1,084,227

6.

Shared Voting Power
-0-

7.

Sole Dispositive Power
1,759,171

8.

Shared Dispositive Power
-0-

9.

Aggregate Amount Beneficially Owned by Each Reporting Person
1,759,171

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions). o

11.

Percent of Class Represented by Amount in Row (9)
6.7%

12.

Type of Reporting Person (See Instructions)
IN

CUSIP No. 503459604

Item 1.

(a)

Name of Issuer:
La Jolla Pharmaceutical Company

(b)

Address of Issuers Principal Executive Offices:
4550 Towne Centre Court, San Diego, CA 92121, United States

Item 2.

(a)

Name of Person(s) Filing:
Sectoral Asset Management Inc.

Jérôme G. Pfund

Michael L. Sjöström

(b)

Address of Principal Business Office or, if none, Residence:
The principal business address of each person filing is:

1610-1010 Sherbrooke St. West, Montreal QC, H3A 2R7 Canada

(c)

Citizenship:
Sectoral Asset Management Inc. is a Canadian corporation

Jérôme G. Pfund is a Swiss citizen

Michael L. Sjöström is a Swiss citizen

(d)

Title of Class of Securities:
Common Stock

(e)

CUSIP Number:
503459604

Item 3.

If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

(a)

o

Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).

(b)

o

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

(c)

o

Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c).

(d)

o

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8).

(e)

x

An investment adviser in accordance with §240.13d-1(b)(1)(ii)(E);

(f)

o

An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F);

(g)

x

A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h)

o

A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

o

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j)

o

A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J);

(k)

o

Group, in accordance with § 240.13d-1(b)(1)(ii)(K). If filing as a non-U.S. institution in accordance with

§ 240.13d-1(b)(1)(ii)(J), please specify the type of institution: ____________________________

CUSIP No. 503459604

Ownership.

Sectoral Asset Management Inc, in its capacity as an investment adviser, has the sole right to dispose of or vote the number of shares of common stock of the Issuer set forth in this filing.  Jérôme G. Pfund and Michael L. Sjöström, together, hold majority of shares of Sectoral Asset Management Inc.  Sectoral Asset Management, Inc. and Messrs. Pfund and Sjöström disclaim beneficial ownership of the Issuers common stock held by Sectoral Asset Management Inc.

(a)

Amount beneficially owned:   

Sectoral Asset Management Inc.: 1,759,171 shares

Jérôme G. Pfund:  1,759,171 shares

Michael L. Sjöström:  1,759,171 shares

(b)

Percent of class:

Sectoral Asset Management Inc.:  6.7%

Jérôme G. Pfund:  6.7%

Michael L. Sjöström:  6.7%

(c)

Number of shares as to which the person has:

(i)

Sole power to vote or to direct the vote:   

Sectoral Asset Management Inc.:  1,084,227 shares

Jérôme G. Pfund:  1,084,227 shares

Michael L. Sjöström:  1,084,227 shares

(ii)

Shared power to vote or to direct the vote:    

Sectoral Asset Management Inc.: -0- shares

Jérôme G. Pfund:  -0- shares

Michael L. Sjöström:  -0- shares

(iii)

Sole power to dispose or to direct the disposition of:   

Sectoral Asset Management Inc.:  1,759,171 shares

Jérôme G. Pfund:  1,759,171 shares

Michael L. Sjöström:  1,759,171 shares

(iv)

Shared power to dispose or to direct the disposition of:   

Not applicable.

CUSIP No. 503459604

Dated: February 12, 2019

SECTORAL ASSET MANAGEMENT INC.

/s/Marc-Andre Marcotte

By:

Marc-Andre Marcotte

Its:

Chief Operating Officer

Dated: February 12, 2019

/s/Jérôme G. Pfund

Jérôme G. Pfund

Dated: February 12, 2019

/s/Michael L. Sjöström

Michael L. Sjöström

CUSIP No. 503459604

SECTORAL ASSET MANAGEMENT INC.

/s/ Marc-Andre Marcotte

By:

Marc-Andre Marcotte

Its:

Chief Operating Officer

/s/Jérôme G. Pfund

Jérôme G. Pfund

/s/Michael L. Sjöström

Michael L. Sjöström