Xenon Pharmaceuticals Inc. (XENE)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Fmr Llc	7,525,290	$294,991,368	0.01%
2.	Wellington Management Group Llp	3,777,611	$148,082,351	0.02%
3.	Henderson Group Plc	2,866,755	$112,425,225	0.05%
4.	Capital International Investors	2,547,210	$99,850,632	0.01%
5.	Capital World Investors	2,294,537	$89,945,850	0.01%