Spyre Therapeutics Inc. (SYRE)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Fmr Llc	8,801,266	$204,893,472	0.01%
2.	Fairmount Funds Management Llc	4,018,101	$93,541,391	9.29%
3.	Rtw Investments, Llc	3,621,996	$84,320,067	1.27%
4.	Blackrock, Inc.	3,399,591	$79,142,479	0%
5.	Vanguard Group Inc	2,846,473	$66,265,892	0%