| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 3,069,225 | $100,547,811 | +150% | 1.79% |
| 2. | Driehaus Capital Richard Driehaus | 2,882,420 | $94,428,079 | +40% | 0.64% |
| 3. | Commodore Capital Egen Atkinson And Michael Kramarz | 2,388,245 | $78,238,906 | +21% | 5.21% |
| 4. | Tang Capital Management Kevin C. Tang | 1,892,200 | $61,988,472 | -41% | 3.06% |
| 5. | Braidwell LP Alex Karnal | 1,634,615 | $53,549,987 | -37% | 1.71% |