Spruce Biosciences Inc. (SPRB)

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Institutional Investors' Holdings

Filing Period:

No.	Name	Shares	Value	% Port
1.	Novo A/s	6,722,336	$19,696,444	1.21%
2.	Rivervest Venture Management Llc	2,936,281	$8,603,304	31.72%
3.	Carlyle Group L.p.	2,896,518	$8,370,937	0.4%
4.	5am Venture Management, Llc	2,364,000	$6,926,520	1.83%
5.	Omega Fund Management, Llc	2,161,022	$6,331,794	5.12%