| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | VenBio Select Advisor Kurt Von Emster | 2,900,000 | $134,270,000 | +13% | 1.32% |
| 2. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 1,314,002 | $60,838,293 | +53% | 2.01% |
| 3. | Millennium Management Israel Englander | 1,236,321 | $57,241,662 | +27% | 0.02% |
| 4. | Commodore Capital Egen Atkinson And Michael Kramarz | 1,200,000 | $55,560,000 | -12% | 3.7% |
| 5. | Braidwell LP Alex Karnal | 1,187,859 | $54,997,872 | -8% | 1.76% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.00 | 250,000 | $5,000,000.00 | 3,074,542 | 2023-09-28 | Filing | |
| $21.00 | 36,939 | $775,719.00 | 2,824,542 | 2023-09-26 | Filing | |
| $20.03 | 117,996 | $2,363,459.88 | 2,787,603 | 2023-09-26 | Filing | |
| $19.11 | 88,685 | $1,694,770.35 | 2,669,607 | 2023-09-26 | Filing | |
| $18.24 | 52,691 | $961,083.84 | 2,580,922 | 2023-09-26 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $82.76 | 3,830 | $316,970.80 | 13,206 | 2025-07-01 | Filing | |
| $84.25 | 266 | $22,410.50 | 17,036 | 2025-06-24 | Filing | |
| $70.11 | 3,782 | $265,156.02 | 27,036 | 2025-04-01 | Filing | |
| $71.55 | 5,937 | $424,797.10 | 6,500 | 2025-03-28 | Filing | |
| $66.95 | 23,475 | $1,571,716.98 | 28,143 | 2025-03-27 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 8,079,304 | $374,071,758 | 0.02% | |
| 2. | 7,178,354 | $332,302,144 | 0.15% | |
| 3. | 3,871,639 | $179,256,886 | 0% | |
| 4. | 3,322,799 | $153,845,595 | 0.03% | |
| 5. | 3,060,361 | $141,694,714 | 0% |
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