| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | RA Capital Management Peter Kolchinsky | 6,995,858 | $195,044,521 | 2% | |
| 2. | Driehaus Capital Richard Driehaus | 4,809,470 | $134,088,024 | -3% | 0.91% |
| 3. | Samsara BioCapital Srini Akkaraju And Michael Dybbs | 3,149,128 | $87,797,689 | 9.06% | |
| 4. | Siren L.L.C. Raymond Debbane | 2,000,000 | $55,760,000 | -10% | 1.66% |
| 5. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,720,782 | $47,975,402 | -58% | 1.61% |