| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Perceptive Advisors Joseph Edelman | 0 | $0 | 0% | |
| 2. | Fondren Management Bradley Louis Radoff | 0 | $0 | 0% | |
| 3. | D E Shaw D. E. Shaw | 0 | $0 | 0% | |
| 4. | Biotechnology Value Fund / BVF Inc Mark Lampert | 0 | $0 | 0% | |
| 5. | Tudor Investment Corp Paul Tudor Jones | 0 | $0 | 0% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $3.46 | 10,000 | Director | 10,000 | 2017-06-05 | Filing | |
| $3.37 | 34,614 | Director | 185,709 | 2017-05-25 | Filing | |
| $3.55 | 20,000 | Director | 151,095 | 2017-05-23 | Filing | |
| $3.49 | 23,507 | Director | 131,095 | 2017-05-16 | Filing | |
| $16.26 | 9,120 | Director | 46,560 | 2015-09-30 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $0.60 | 11,117 | Officer | 66,807 | 2018-12-24 | Filing | |
| $2.01 | 927 | Officer | 40,670 | 2018-10-10 | Filing | |
| $2.02 | 927 | Officer | 59,734 | 2018-10-10 | Filing | |
| $2.01 | 1,156 | Officer | 77,924 | 2018-10-10 | Filing | |
| $2.02 | 1,156 | Officer | 51,754 | 2018-10-10 | Filing |
