| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Propel Bio Management Leen Kawas And Richard Kayne | 4,118,321 | $8,319,008 | -20% | 7.1% |
| 2. | Adage Capital Management Phill Gross And Robert Atchinson | 2,810,037 | $5,676,275 | -60% | 0.01% |
| 3. | Marshall Wace LLP Paul Marshall And Ian Wace | 1,656,821 | $3,346,777 | +290% | 0% |
| 4. | Lion Point Didric Cederholm | 755,000 | $1,525,100 | +15% | 7.89% |
| 5. | Boxer Capital Aaron Davis And Christopher Fuglesang | 666,666 | $1,346,665 | 0.29% |