| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Darwin Global Management Abhishek Trehan | 12,960,538 | $894,795,544 | +24% | 84.75% |
| 2. | Baker Bros. Advisors Julian Baker And Felix Baker | 5,006,863 | $345,673,822 | +14% | 3.69% |
| 3. | 71,505,000 | $155,248,473 | 0.11% | ||
| 4. | 66,584,000 | $144,306,857 | +8% | 4.16% | |
| 5. | Adage Capital Management Phill Gross And Robert Atchinson | 1,647,562 | $113,747,680 | +60% | 0.19% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $19.29 | 10,000 | Director | 10,000 | 2023-05-15 | Filing | |
| $19.29 | 10,000 | Director | 298,615 | 2023-05-15 | Filing | |
| $17.70 | 10,000 | Director | 15,900 | 2022-11-01 | Filing | |
| $17.53 | 20,000 | Director | 281,021 | 2022-10-31 | Filing | |
| $17.69 | 45,000 | Director | 98,265 | 2022-10-31 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $75.26 | 805 | Officer, Director | 233,924 | 2025-04-01 | Filing | |
| $74.78 | 2,232 | Officer, Director | 234,729 | 2025-04-01 | Filing | |
| $73.44 | 772 | Officer, Director | 236,961 | 2025-04-01 | Filing | |
| $72.29 | 3,021 | Officer, Director | 237,733 | 2025-04-01 | Filing | |
| $77.83 | 2,737 | Officer, Director | 233,924 | 2025-03-17 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 303,557 | $23,158,344 | 0.02% | |
| 2. | 35,704 | $2,723,858 | 0.12% | |
| 3. | 203,000 | $481,212 | 0.07% | |
| 4. | 4,476 | $341,473 | 0.01% | |
| 5. | 1,937 | $147,774 | 0% |
