| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Decheng Capital Min Cui | 6,371,669 | $264,551,697 | 35.59% | |
| 2. | Braidwell LP Alex Karnal | 1,870,571 | $77,666,108 | -44% | 2.48% |
| 3. | OrbiMed Advisors Samuel Isaly | 1,516,550 | $62,967,156 | -13% | 1.29% |
| 4. | Avidity Partners Management David Witzke And Michael Gregory | 1,472,699 | $61,146,462 | -9% | 17.64% |
| 5. | Polar Capital Brian Ashford-Russell And Tim Woolley | 1,098,662 | $45,616,446 | 0.18% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $33.00 | 1,515,151 | $49,999,983.00 | 1,515,151 | 2025-09-11 | Filing | |
| $19.00 | 400,000 | $7,600,000.00 | 4,958,810 | 2024-01-29 | Filing | |
| $19.00 | 1,315 | $24,985.00 | 1,315 | 2024-01-29 | Filing | |
| $19.00 | 2,000 | $38,000.00 | 2,000 | 2024-01-29 | Filing | |
| $19.00 | 263,157 | $4,999,983.00 | 613,928 | 2024-01-29 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $52.99 | 10,491 | $555,918.09 | 0 | 2026-01-09 | Filing | |
| $44.16 | 654 | $28,880.64 | 0 | 2026-01-09 | Filing | |
| $41.43 | 1,000 | $41,430.00 | 0 | 2025-11-17 | Filing | |
| $43.25 | 1,000 | $43,250.00 | 0 | 2025-10-13 | Filing | |
| $43.99 | 5,903 | $259,672.97 | 0 | 2025-10-09 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 6,539,482 | $271,519,293 | 0% | |
| 2. | 5,999,790 | $249,111,280 | 0.04% | |
| 3. | 4,843,242 | $201,091,408 | 0% | |
| 4. | 4,298,173 | $178,460,143 | 0.01% | |
| 5. | 3,670,206 | $152,386,953 | 5.04% |
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