| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,355,257 | $24,611,467 | +1% | 0.83% |
| 2. | Nantahala Capital Management Wilmot B. Harkey And Daniel Mack | 1,235,000 | $22,427,600 | 0.74% | |
| 3. | OrbiMed Advisors Samuel Isaly | 1,187,300 | $21,561,368 | -13% | 0.44% |
| 4. | Caligan Partners David Johnson | 881,533 | $16,008,639 | +6% | 1.32% |
| 5. | RA Capital Management Peter Kolchinsky | 662,968 | $12,039,499 | 0.12% |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $13.00 | 500 | $6,500.00 | 1,000 | 2024-11-13 | Filing | |
| $12.50 | 500 | $6,249.50 | 500 | 2024-11-12 | Filing | |
| $0.62 | 182,300 | $113,026.00 | 0 | 2023-06-26 | Filing | |
| $0.64 | 1,425,700 | $917,152.81 | 0 | 2023-06-26 | Filing | |
| $4.14 | 2,000 | $8,288.80 | 1,425,700 | 2023-06-20 | Filing |
| Insider | Price | Amount | Total Value | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $14.35 | 8,200 | $117,648.68 | 0 | 2025-11-14 | Filing | |
| $14.30 | 3,167 | $45,288.10 | 0 | 2025-11-14 | Filing | |
| $0.52 | 937,404 | $486,887.64 | 731,458 | 2023-06-27 | Filing | |
| $0.61 | 2,746,138 | $1,682,009.53 | 1,668,862 | 2023-06-26 | Filing | |
| $3.98 | 1,270 | $5,054.60 | 0 | 2018-08-13 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 1,051,054 | $19,087,141 | 1.09% | |
| 2. | 804,084 | $14,602,165 | 0% | |
| 3. | 621,350 | $11,283,716 | 0% | |
| 4. | 483,000 | $8,771,280 | 0.29% | |
| 5. | 477,816 | $8,677,138 | 0% |
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