| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | EcoR1 Capital Oleg Nodelman | 6,726,491 | $165,673,473 | 5.67% | |
| 2. | Citadel Investment Group Ken Griffin | 2,707,551 | $66,686,981 | +3% | 0.01% |
| 3. | Avidity Partners Management David Witzke And Michael Gregory | 1,497,000 | $36,871,110 | -50% | 1.88% |
| 4. | Braidwell LP Alex Karnal | 1,284,472 | $31,636,545 | +149% | 0.89% |
| 5. | Opaleye Management James A. Silverman | 1,255,000 | $30,910,650 | +127% | 5.15% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $70.00 | 142,857 | Director | 822,857 | 2020-12-18 | Filing | |
| $23.99 | 8,333 | Director | 42,718 | 2020-11-09 | Filing | |
| $30.26 | 2,000 | Director | 79,546 | 2020-06-17 | Filing | |
| $32.30 | 3,000 | Director | 77,546 | 2020-06-02 | Filing | |
| $38.18 | 2,500 | Director | 29,520 | 2020-03-24 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $27.69 | 231 | Officer | 8,040 | 2024-11-07 | Filing | |
| $17.05 | 229 | Officer | 8,271 | 2023-11-08 | Filing | |
| $47.05 | 5,196 | Officer, Director | 1,036,681 | 2024-02-23 | Filing | |
| $47.05 | 1,702 | Officer | 181,916 | 2024-02-23 | Filing | |
| $47.05 | 1,699 | Officer | 67,516 | 2024-02-23 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 5,354,864 | $220,406,204 | 0% | |
| 2. | 4,851,390 | $199,683,213 | 0% | |
| 3. | 4,213,483 | $173,426,960 | 2.7% | |
| 4. | 2,507,731 | $103,218,208 | 1.57% | |
| 5. | 2,244,019 | $92,363,838 | 0% |
