| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Farallon Capital Thomas Steyer | 5,660,866 | $251,512,276 | +1% | 1.23% |
| 2. | Armistice Capital Steven Boyd | 2,207,070 | $98,060,120 | +7% | 1.56% |
| 3. | Marshall Wace LLP Paul Marshall And Ian Wace | 1,263,285 | $56,127,753 | +12% | 0.06% |
| 4. | Biotechnology Value Fund / BVF Inc Mark Lampert | 1,190,107 | $52,876,454 | 1.54% | |
| 5. | Polar Capital Brian Ashford-Russell And Tim Woolley | 1,002,036 | $44,520,459 | 0.21% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $31.00 | 40,322 | Officer, Director | 41,722 | 2019-11-13 | Filing | |
| $31.00 | 8,064 | Director | 97,567 | 2019-11-13 | Filing | |
| $31.00 | 403,225 | Large Shareholder | 1,777,824 | 2019-11-12 | Filing | |
| $83.44 | 200 | Director | 571 | 2018-03-16 | Filing | |
| $67.00 | 851,154 | Large Shareholder | 1,374,599 | 2018-01-23 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $56.09 | 772 | Officer | 813 | 2024-11-08 | Filing | |
| $59.21 | 1,500 | Director | 7,992 | 2024-11-08 | Filing | |
| $58.57 | 4,929 | Director | 9,492 | 2024-11-08 | Filing | |
| $57.24 | 3,571 | Director | 14,421 | 2024-11-08 | Filing | |
| $54.41 | 1,868 | Director | 7,992 | 2024-11-07 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 5,527,438 | $123,096,044 | 0% | |
| 2. | 4,962,237 | $110,509,016 | 0% | |
| 3. | 4,011,000 | $89,324,970 | 1.36% | |
| 4. | 2,625,685 | $58,474,005 | 0% | |
| 5. | 2,596,764 | $57,831,549 | 0.01% |
