| No. | Hedge Fund | Shares | Value | Activity | % Port |
|---|---|---|---|---|---|
| 1. | Deerfield Management James E. Flynn | 9,127,305 | $141,381,954 | -1% | 2.35% |
| 2. | Renaissance Technologies Jim Simons | 2,175,727 | $33,702,011 | +16% | 0.05% |
| 3. | Royce & Associates Chuck Royce | 2,162,022 | $33,489,721 | +4% | 0.31% |
| 4. | Marshall Wace LLP Paul Marshall And Ian Wace | 1,219,537 | $18,890,629 | -28% | 0.02% |
| 5. | Opaleye Management James A. Silverman | 640,000 | $9,913,600 | -37% | 2.26% |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $2.99 | 7,000 | Director | 560,376 | 2020-09-30 | Filing | |
| $2.97 | 15,000 | Officer, Director | 4,787,693 | 2020-09-30 | Filing | |
| $4.70 | 10,000 | Director | 553,376 | 2019-10-11 | Filing | |
| $4.89 | 10,000 | Officer, Director | 4,772,693 | 2019-10-03 | Filing | |
| $3.23 | 25,000 | Officer, Director | 4,762,693 | 2019-06-11 | Filing |
| Insider | Price | Amount | Relationship | Remaining Holdings | Date | Form 4 |
|---|---|---|---|---|---|---|
| $20.10 | 15,000 | Director | 348,874 | 2024-08-21 | Filing | |
| $20.59 | 50,000 | Officer | 675,124 | 2024-08-20 | Filing | |
| $20.21 | 50,000 | Officer | 725,124 | 2024-08-20 | Filing | |
| $20.26 | 50,000 | Officer | 775,124 | 2024-08-20 | Filing | |
| $18.42 | 30,000 | Officer | 12,369 | 2024-08-09 | Filing |
| No. | Name | Shares | Value | % Port |
|---|---|---|---|---|
| 1. | 15,822,299 | $265,972,852 | 0% | |
| 2. | 7,120,417 | $119,694,211 | 0% | |
| 3. | 6,787,332 | $114,095,051 | 0% | |
| 4. | 2,601,797 | $43,737,912 | 0.01% | |
| 5. | 2,200,225 | $36,990,038 | 0% |
