Top 5 Most Profitable Pharmaceutical Companies In The World

2. GSK plc (NYSE:GSK)

2022 Net Income: $18.49 billion

2022 Revenue: $36.27 billion  

GSK plc (NYSE:GSK) underwent significant transformations in 2022, including a rebranding as GSK and the spinoff of Haleon. The company achieved an overall growth rate of 13%, fueled by the success of Shingrix and its HIV medications. GSK plc (NYSE:GSK)’s COVID antibody Xevudy generated sales of 2.3 billion pounds ($3.17 billion), although it lost authorization in the U.S. The oncology segment faced challenges with Zejula and Blenrep, but GSK made strategic investments in ADCs and acquired Sierra Oncology. Jemperli showed promising results in lung cancer treatment.