Top 5 Drug Companies in the US by Revenue

2. Johnson & Johnson (NYSE:JNJ)

2022 Revenue: $94.9 billion

Established in 1886, Johnson & Johnson is a leading pharmaceutical company not only in the United States but also globally. Stelara, used to treat plaque psoriasis, psoriatic arthritis, Crohn’s disease and ulcerative colitis, has been the company’s top-selling drug since 2019, with sales reaching $9.7 billion in 2022.

On October 17, Johnson & Johnson (NYSE:JNJ) posted earnings for the third quarter of 2023, reporting a NON-GAAP EPS of $2.66, beating market estimates by $0.14. The revenue over the period was $21.35 billion, up 6.8% compared to the revenue over the same period last year.