Top 5 Drug Companies in the US by Revenue

3. Merck & Co., Inc. (NYSE:MRK)

2022 Revenue: $59.3 billion

Merck & Co., Inc. (NYSE:MRK) is a Rahway, New Jersey-based pharmaceutical company which develops medicines, vaccines, biologic therapies, and animal health products. With sales of almost $21 billion, immunotherapy medication Keytruda was the company’s best-selling product in 2022.

According to Insider Monkey’s second quarter database, 78 hedge funds were bullish on Merck & Co., Inc. (NYSE:MRK), compared to 75 funds in the preceding quarter. Cliff Asness’ AQR Capital Management held the largest position in the company, with approximately 2.91 million shares valued at $331.84 million.