Top 5 Best-Selling Cancer Drugs

2. Revlimid 

Total Sales: 22.8 billion 

Revlimid (lenalidomide), standing second among the top best-selling cancer drugs, is an immunomodulatory drug widely used for treating multiple myeloma, bone marrow disorders, and myelodysplastic syndrome. FDA-approved in combination with dexamethasone for newly diagnosed multiple myeloma, it has shown effectiveness. However, clinical trials indicate an increased risk of developing certain cancers like acute myelogenous leukemia. Financially, Revlimid has been a top-selling cancer drug, generating over $20 billion in annual sales.