2. Colorado Springs, Colorado
Annual rate: 26.1 per 100,000 people annually
The unemployment in Colorado Springs is higher than the state’s. It may come as a surprise to you, but altitude is intimately related to the suicide rates of this city. Oxygen deprivation is believed to worsen depression, a common mental disease that may lead to self-inflicted termination of life, and may help explain while Colorado has two of the most suicidal cities in the country.
