10. Karthus
Games Played: 67,627
Games Won: 34,665
Games Lost: 32,962
Winning Percentage: 51.25%
Karthus’ ultimate is both much-loved (by his team) and much-maligned (by his opponents), and as you can see, he is rarely played despite a notable winning percentage of over 51%. Despite that, Karthus suffers from having only one real damage skill (his other is an aura skill), and building him requires all manner of attention paid to different stats, including his tankiness so he can get close with that aura and his short-range Q, and his cooldown so he can more often use that loved and maligned ult.