Revance Therapeutics, Inc. (NASDAQ:RVNC) Q1 2024 Earnings Call Transcript

Revance Therapeutics, Inc. (NASDAQ:RVNC) Q1 2024 Earnings Call Transcript May 9, 2024

Revance Therapeutics, Inc. isn’t one of the 30 most popular stocks among hedge funds at the end of the third quarter (see the details here).

Operator: Welcome to the Revance Therapeutics First Quarter2024 Financial Results and Corporate Update Conference Call. At this time, all participants are in a listen-only mode. [Operator Instructions]. As a reminder, this call is being recorded today, Thursday, May 9, 2024. I would now like to turn the conference call over to Laurence Watts of New Street Investor Relations. Please go ahead. Laurence Watts Thank you, operator. Joining us on the call today from Revance are President and Chief Executive Officer, Mark Foley, and Chief Financial Officer, Toby Schilke. During this call, management will make forward-looking statements, including statements related to the impact of our pricing and strategy on DAXXIFY on adoption; expectations related to product adoption, account activation and reorders; consumer needs, preferences, and behavior; the benefits and value to us, practices, and consumers of our product, including the efficacy, duration, skin quality, and safety of our products; access to our products; future therapeutic indications; 2024 guidance; cash flow breakeven; positive adjusted EBITDA; future capital expenditures; anticipated revenue and top line growth; our strategic priorities; our anticipated success; our blockbuster potential; our ability to grow and take share; our market opportunity and expectations; our strategy, planned operations, and commercialization plans, including consumer offers and timing of those plans.

Our actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties. Factors that could cause these results to be different from these statements, include factors the company describes in the section called Risk Factors in our in our annual report on Form 10-K and our quarterly report on Form 10-Q. Revance undertakes no duty or obligation to update any forward-looking statements as a result of new information, future events or changes in its expectations. Also on today’s call, we will present both GAAP and non-GAAP financial measures. Reconciliations of GAAP to non-GAAP measures are included in our earnings release. With that, I will turn the call over to Mark Foley, President and Chief Executive Officer of Revance.

Mark?

Mark Foley: Thank you, Lawrence. Good afternoon, everyone, and thank you for joining our first quarter 2024 financial results conference call. Q1 2024 was the second full quarter reflecting DAXXIFY’s strategy change and we are encouraged by the ongoing traction and momentum that we are seeing related to this change. Specifically, DAXXIFY aesthetic units sold were up 105% year-over-year and notably up 7% on a quarter-over-quarter basis, despite Q1 traditionally being a seasonally down quarter when compared to Q4. Moreover, DAXXIFY grew its market share from 3% at the end of Q4 2023 to 3.7% at the end of Q1 2024, highlighting not only its ability to grow, but also take share. In the first quarter, DAXXIFY net revenue was $22.1 million after a reduction of $2 million related to our consumer coupon program, which functioned like a rebate.

While we were encouraged by the feedback we received on the consumer coupon program, we will look to structure future offerings in a way that doesn’t require a full revenue offset, and that is more consistent with competitor programs from a revenue treatment and sales and marketing expense perspective. Importantly, feedback from the field continues to be positive and reveals that practices are re-engaging with DAXXIFY not only because of its duration profile, but also because of its fast onset and improved skin quality, which is made possible by its unique and differentiated peptide formulation. To that end, in the quarter, I was able to personally meet with over 200 injectors across a variety of regional dinners and office visits, and I was very encouraged by the receptivity, feedback, and support we are getting as a result of our new strategy.

With our reduced price to the practice, we are encouraged to see that accounts are passing along the savings to their patients, thereby allowing them to experience DAXXIFY’s performance benefits at a price that is in line with other toxins. At the end of the day, customers are reporting that they are choosing to lean in with DAXXIFY because they feel it is a better product. In the quarter, we also launched a new DAXXIFY messaging campaign titled, The DAXXIFY Difference – Fast. Lasts. And the Look. And we removed the no advertised price limitation, which has allowed accounts to more easily promote DAXXIFY to their customers and which will help further amplify DAXXIFY’s voice in the market. Consistent with prior commentary, our last two quarters were focused on existing DAXXIFY accounts in order to reestablish confidence and a more positive relationship going forward.

We believe that this focus was necessary to build the right foundation for long-term success. Now that we have concluded this phase, we expect a return to a more normal new account cadence and portfolio focus. In the quarter, we were also encouraged by the strong reordering activity as existing accounts represented more than two-thirds of DAXXIFY revenue in the quarter, the higher average order size per account representing deeper penetration, consumer end pricing coming in line with competitor prices reflecting that the strategy change is having the desired effect, all of which has contributed to a meaningful uptick in unit sales on both an annual and quarterly basis as well as a healthy gain in market share. Turning to RHA, despite filler market softness in Q1 and outside DAXXIFY focus, we continued to grow our filler market share and ended Q1 with a 9.8% share, up from 9.1% in Q4.

While RHA revenue declined 2% year-over-year, our ability to take share in a soft filler quarter positions us well going forward, particularly as the market returns to more normal growth, we launch some of our new initiatives, and as our focus shifts to a more balanced portfolio approach. Underpinning our ongoing market share gains and traction in the filler market is the quality and differentiated performance profile of the RHA portfolio, combined with our commercial team’s ability to execute. As we move into Q2, we are excited to be launching RHA 3 for lip augmentation and fullness, as lips are the number one filler procedure performed in the US. And while Q1 revealed some softness in the US filler market, we expect the market to return to historic high-single-digit growth through the balance of 2024.

To this end, we are encouraged by the early traction and momentum we are seeing in Q2 related to both the filler and toxin markets. Lastly, at the end of the first quarter, there were over 7,500 aesthetic accounts, of which 3,500 have ordered DAXXIFY, which leaves us with significant runway to further expand our number of accounts and ordering base going forward. Now let me turn to our therapeutic franchise. This afternoon, we announced the commercial launch of DAXXIFY for the treatment of cervical dystonia, marking our entry into the $2.7 billion US therapeutic neurotoxin market, which is projected to grow 8% annually over the next five years. DAXXIFY is the first and only peptide-formulated long-lasting neurotoxin that offers the potential to improve duration of symptom control with a favorable safety profile, providing patients and physicians with a compelling new treatment option for a painful and disabling chronic condition.

DAXXIFY for cervical dystonia provides a significant opportunity for Revance and marks the culmination of our decades-long mission to bring true innovation to the therapeutics market. While toxins are the gold standard of care for cervical dystonia, patients struggle to achieve sustained symptom relief in between treatments. This is due to the fact that toxin treatment can only occur every 12 weeks based on product labeling and reimbursement guidelines, even though the therapeutic benefit of current toxins typically wears off 8 to 10 weeks after injection. As a result, this frequently leaves patients with unmanaged symptoms that can lead to significant pain, social stigma, and the inability to drive or work. DAXXIFY has the potential to offer CD patients more good days and better symptom control in between treatments, ending the rollercoaster ride that many cervical dystonia patients experience.

Following our CD approval in August of 2023, we launched the PrevU early experience program with the objective of optimizing treatment outcomes and ensuring smooth practice integration. To date, real-world clinical results from PrevU, which has now ceased enrollment as we move into our full launch, are in line with our prior ASPEN clinical program, providing us with a strong foundation for commercial success. The program enrolled over 300 patients, most of which are now on their second treatment cycle. Based on a survey we conducted, which included all 17 physicians who participated in the PrevU program since inception, 94% indicated that they perceived DAXXIFY to last longer than what they had seen with conventional botulinum toxins based on just their first treatment cycle experience and prior to dose optimization.

Additionally, we’ve been pleased to see the DAXXIFY safety profile continues to be encouraging over a broad range of doses. We look forward to sharing some of our PrevU insights at upcoming medical meetings. Post-approval, we established our therapeutics commercial infrastructure in preparation for launch and received our permanent J-code, which will streamline the reimbursement pathway for providers. Also, we operationalized our Access DAXXIFY reimbursement support services in order to minimize potential hurdles to adoption. Within that platform, we have tools and resources to support practices, including our patient affordability programs, a copay program for the underinsured, and a patient assistance program to ensure out-of-pocket costs do not impede access to therapy.

Currently, DAXXIFY is covered for over 78% of commercial lives, which, when combined with our government coverage, represents over 200 million lives and includes the top health plans in the US. We are energized by our mission to positively impact the lives of cervical dystonia patients and believe that we have the right payer infrastructure in place to facilitate the smooth switch process. That said, given the conservative nature of the treating physicians and CD market size, we anticipate initial revenues will be modest. However, we remain bullish regarding DAXXIFY’s potential in the cervical dystonia market and subsequent therapeutic indications and our preview results have only helped to further increase our confidence in DAXXIFY’s long-term potential in the therapeutics market.

Before I turn the call over to Toby to cover our first quarter financials, I want to highlight the progress we’re making on one of our other 2024 strategic priorities, namely, focused and disciplined capital allocation. In conjunction with our DAXXIFY strategy change, we’ve implemented a number of OpEx efficiency measures designed to both streamline and lower our overall operating expense profile while also ensuring that we can free up the necessary capital to invest in both our aesthetics and therapeutics franchises. I’m pleased to report that we are ahead of plan with respect to these efforts, and Toby will touch on that shortly. With over $275 million in cash, cash equivalents, and investments at the end of Q1, the ongoing growth and opportunity we have with DAXXIFY and RHA, and initiatives in place for the second quarter and balance of the year, we are reiterating our guidance, which includes net product revenue of at least $280 million, non-GAAP OpEx of $290 million to $310 million, which is currently trending to the low end of the range, and our goal of reaching positive adjusted EBITDA in 2025.

With that, I’ll turn the call over to Toby to cover our first quarter financials.

Tobin Schilke : Thank you, Mark. The press release and the 10-Q we issued today details our financial results in full. So I will only go over the highlights on this call. Our Fintech Platform business, which was our legacy service segment, is now a discontinued operation and is reflected as such on our financial statements. Consequently, the results that I will discuss exclude discontinued operations. Total revenue for the first quarter ended March 31st, 2024 was $51.9 million compared to $45.8 million for the same period last year, representing a 13% increase in revenue due to DAXXIFY. Net revenue for the first quarter included $29.6 million of RHA Collection revenue, $22.1 million of DAXXIFY revenue and $0.2 million of collaboration revenue related to our biosimilar to Botox program with Viatris.

Total operating expenses from continuing operations for the first quarter were $98.8 million compared to $92.5 million for the same period in 2023. Excluding cost of product revenue, stock-based compensation, depreciation and amortization, non-GAAP operating expenses from continuing operations for the first quarter were $73.6 million compared to $64.5 million for the same period in 2023. As Mark alluded to, we are reiterating our guidance for 2024 and specifically related to our non-GAAP OpEx guidance of $290 million to $310 million, we are currently trending to the low end of that range due to cost savings and other efficiency initiatives. On the balance sheet side, our current cash position, bolstered by an equity offering in the first quarter, which resulted in gross proceeds of $100 million, in combination with our operating plan, provides us with multiple levers to achieve positive adjusted EBITDA in 2025.

Finally, Revance’s shares of common stock outstanding as of April 30th, 2024 were approximately 104.4 million with approximately 113.5 million fully diluted shares, excluding the impact of convertible debt. And with that, I’ll turn the call back over to Mark.

Mark Foley : Thank you, Toby. For the rest of 2024, we remain focused on delivering at least 32% top line growth, while effectively managing spend to reach positive adjusted EBITDA in 2025. We believe this is achievable through successful execution on our DAXXIFY and RHA growth initiatives in aesthetics, our launch of DAXXIFY in cervical dystonia, and through maintaining disciplined capital allocation while ensuring we have the necessary resources to fund our two franchises. We remain encouraged by our ongoing market share gains across both DAXXIFY and RHA, and the positive response we are seeing to DAXXIFY strategy change as reflected by the significant increase in unit volume on a year-over-year and quarterly basis. As a result, we continue to have conviction in our blockbuster potential in the US aesthetics market. With that, I will now open the call up for questions. Operator?

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Q&A Session

Operator: [Operator Instructions]. The first question comes from Seamus Fernandez with Gugenheim.

Seamus Fernandez: Mark, I just wanted to get a better sense of the trajectory that you’re already seeing in the second quarter so far. Obviously, the $22 million would have been $24 million without the couponing program, but presumably you knew about the couponing dynamics. So just trying to get a better sense of the trajectory that you’re seeing. I know that the plan was to accelerate to expand the number of injectors in the second quarter with a full push after you had really reestablished the pricing. So just wanted to get a better sense of what you’re seeing so far in these first five weeks of the second quarter to give you confidence that $280 million minimum guidance threshold is achievable. The second part of that question also related to guidance is just the filler dynamics.

Obviously, we’re seeing a lot of pushes and pulls there, but you do have the launch of the new sort of lip formulation, RH 3. So can you just help us understand what you see as the incremental revenue opportunity there just given the sort of high frequency of lip filler use.

Mark Foley: Seamus, let me start with the first one in terms of our confidence in the product revenue guidance of at least $280 million. As you noted, we were very pleased with the DAXXIFY performance in Q1. And as we’ve made the shift in the pricing change, it’s all about getting trial usage and experience because we believe that the more accounts and consumers that get exposed to DAXXIFY and its performance attributes, not just duration, but skin quality and onset, that’s where the stickiness creates. And obviously, we’re trying to build a growing base of accounts and customers. And we saw that pull through at the account level where we saw more accounts ordering larger quantities, which is a good early sign for us. When we kind of looked through the course of the year, we would expect to have sequential growth throughout the year, certainly on the DAXXIFY side as we layer in more accounts.

And given our outsized focus on DAXXIFY the first two quarters and doubling back, we would expect that new account adds will start to elevate as we move towards the remainder of the year. In terms of what we’re seeing in Q2, there’s typically a cadence in terms of the quarterly phasing or the monthly phasing in a quarter. First month of the quarter tends to be the lightest, followed by the second, and followed by the third. But we’re seeing good volumes in at least the accounts that we are in through April and the early part of May across both the toxin and notably the filler side of it. It’s probably hard to tell right now, on the filler side of it, how much of that is our launch of the lip indication because, as you mentioned, that’s certainly going to be a tailwind for us.

And we have some other initiatives that will be rolling out through the balance of the year around portfolio plans and other practice-based initiatives designed to reward engagement and volume. And so, we like what we’re seeing early on in Q2 from that perspective. Again, I do think given that lips are the number one indication, that helps. And I do think our reps now are spending more time with a balanced selling approach, not just more DAXXIFY focused. So it’s early. But, again, if you go back to the market share gains that we saw in Q1, we really like our positioning and our ability to continue to take share. So we continue to feel very good about how we think the rest of the year is going to play out.

Seamus Fernandez: Maybe just a final question. On the therapeutic side, you continue to guide pretty conservatively in terms of how to think about the therapeutic contribution in 2024. But given all the progress that you’ve made with the J-code and the opportunity for reimbursement, how do you feel your position? Do you feel your positions to perhaps do better this year from a therapeutics perspective, to be able to deliver on that guidance or is the guidance from your perspective pretty locked and loaded as it relates to the aesthetics business and you just feel good about the trajectory of the business on aesthetics and you should think about therapeutic as predominantly incremental?

Mark Foley: Yeah, I think it’s the latter. Again, we are very encouraged by what we’re seeing in the therapeutics business, particularly based on the PrevU engagement. Taking the measured approach that we did not only gave us really good feedback from the clinicians, but it allowed us to really put in place the entire kind of reimbursement process from the J-code to the coverage of the commercial level to patient access programs. And so, given that it’s a buy and build product in these practices, that’s why you don’t get those sort of early stocking orders. They want to treat a few patients, make sure that they can get paid, start conservatively with dosing, and then figure out how to optimize. But we believe that once they get through that early phase, which will take a little bit, then we would expect to see meaningful share gains on that.

I think if you time out 2024, as accounts start to work through that phase, we will certainly see some that lean in more aggressively early, but we think most are going to kind of go through that. So we would expect much more meaningful contribution as we move into 2025. But it’s more, as you said, we expect aesthetics is going to carry a big chunk of this year and that therapeutics will be incremental. We could be surprised a little bit on the upside, but that’s how we’re thinking about it from our internal modeling.

Operator: The next question comes from Stacy Ku with TD Cowen.

Stacy Ku: Congrats on the progress. We have a few follow-ups. On the first question, can you just talk about your evolving thoughts on the RHA contribution this year? And to ask a little bit more specifically, if we take your guidance, we do need to see strong growth over the next few quarters. So if we understand kind of how Q1 looks, it looks like it’s at similar levels to last year. So just help us feel comfortable with your belief that we could meaningly grow beyond 2023 RHA sales? Is it really that RHA 3 launch is really going to kind of increase share there? The second question is, looking to Q2, previously, you’ve discussed it takes around a quarter for an account to sample and try DAXXIFY before ordering. So just help us set expectations in terms of the timing of sales acceleration versus a usual lift – seasonality lift that you’ll see in the aesthetic market for Q2.

That’s the second question, just kind of the dynamics between broadening the accounts versus the normal time for sampling. The last question, just curious if you’re willing to comment, as you discussed your plans of going broader and deeper, of the accounts that you’ve already onboarded for DAXXIFY, can you talk about what percentage have made it their primary neurotoxin in their practice versus just one of the offerings? I’m just curious how you’re doing as you go deeper with some of the relationships.

Mark Foley: Let me kind of walk through these. So, first, in terms of kind of how we think again about the cadence of revenue and what you’d need to see in terms of growth and what’s going to drive that, listen, Q1 was softer on the filler side than what we expected. If you look at it, we actually had pretty healthy share growth, even with, again, an outsized focus on DAXXIFY. So I think we’re continuing to take share based on the quality of the product. We expect the market will return to more normal high-single-digit growth. And so, we believe that will also be a tailwind for us as we continue to share with RHA. Previously, when we’ve given contextual guidance to our more than $280 million in product, we said a little more than half of that’s going to be RHA.

And so, if you kind of look at what that means from a year-over-year growth perspective, you can kind of get there in sort of a teens growth on RHA, which we think is manageable, particularly when you start layering in the RHA 3 for lips, some of the promos that we’re going to run around that, the fact that it’s the number one performed for filler procedure. And then we do expect to start to benefit from some portfolio programs based on our broader account base in ways that we will be able to leverage one product with the other to incentivize further leaning in. And so, that’s kind of how we think about that. And as I said, I know it’s early, but we like what we’re seeing in April. And I’m sure some of that is the lips, but I think some of that’s the team, again, turning their focus to broader portfolio as well.

In terms of – let’s see – Q2 and how we think about the time it takes for a new account to fully get up to speed and on board. Yeah, it’s probably a quarter or two. There are still some that are going to want to see a duration signal with DAXXIFY before they fully decide where that fits into their practice, even though we’ve softened the duration message. And what we continue to hear from accounts is, while duration is great, onset and particularly the skin quality continue to be really important differentiators for them. And so, it’s hard for me to say with certainty how those things are all going to knit together when you think about Q2 being a stronger quarter compared to Q1. But when we step back, we have a certain account target of new accounts that we want to add and total accounts that we want to get to by the end of the year using similar utilization metrics.

And frankly, we’ve continued to grow the utilization per account Q4 to Q1. And so, if we can continue that trend and add the new accounts, which we think are very reasonable, that’s how we come up with the numbers that we feel comfortable with. In terms of the broader versus deeper and how we think about adoption, I would say that it’s evolving right now. I’d say it’s certainly a minority of our accounts that have made DAXXIFY their leading and primary toxin, more than 50%. I think it’s a good healthy number where we’re in those accounts, we occupy a decent spot. And our goal is, as they get more familiar and more comfort with it that we can lean in more and continue to increase that penetration, particularly as they get more familiar. And so, again, we have some different initiatives about that, but I would say it’s a small percentage of the accounts that have sort of said DAXXIFY is our primary toxin.

Stacy Ku: Just to follow up, sounds like you are this year, 2024, thinking about maybe implementing – when you say portfolio programs, is that bundling?

Mark Foley: That is. That is correct. We do plan to do that this year in 2024.

Operator: The following question comes from Annabel Samimy with Stifel.

Annabel Samimy: Just following up on the portfolio programs. I guess in terms of the plans that you have in place right now, the coupon you treated as a rebate, are you planning on having portfolio programs as a rebate as well? And I guess what was the – or rather direct savings for those accounts? As we think about the portfolio, have you begun to see more filler ordering from accounts that now have DAXXIFY and vice versa? And are you starting to see that, I guess, account leverage now that you have a portfolio to offer rather than just one product? Switching to therapeutics, in your PrevU program, I was just wondering if the injection frequency – have you noticed whether the injection frequency for these physicians would change, is it still on – do they still plan on injecting on a 12-week basis and just getting better coverage for that patient during those 12 weeks or really extending the time to the next injection because they’re able to?

And just trying to understand whether you’ve seen some stretching out of those second injections. Finally also, are physicians comfortable that this is now the same technique, it’s just more durable with lower adverse events and does that possibly give them comfort to try in other movement disorder indications that they also feel very comfortable using this product?

Mark Foley: First off, on the portfolio programs, we plan to roll those out going forward. So those are early. The consumer coupon that we ran, we wanted to pilot to see, hey, with a consumer coupon, can we incentivize accounts to go deeper with us and offer this to a broader range of their patients, again, with this idea that once they try DAXXIFY, particularly with our new pricing, and get exposed to the benefits of the product that that could result in stickiness. And it was very well received. But since we don’t have a consumer loyalty program set up in some of these other programs, the only way we could really do it was as basically a consumer coupon funneled through the practice that served as a rebate, which is why we had to take the full revenue reversal for that program.

But it gave us good insights and learning. As we think about our portfolio programs going forward, there will be a combination of some price incentives to practices to lean in with us more broadly across the portfolio, and then there’ll be a variety of service offerings. So, we’ve long stated that we’re more focused right now on practice programs that create value for the practices since we think that they’re the best suited to be able to influence switch and choice on the product side of it. And so, we’ll have a variety of other initiatives also linked to portfolio that aren’t just dollars and savings. They might be programs or other value added services that they can benefit from and we will start to roll those out this year. And we would expect given the relationship that we have either with DAXXIFY or RHA that we should be able to create programs that incentivize trial and hopefully adoption given the relationship that we have with the other products.

So we’re excited and encouraged about that. Your question on the therapeutic side with regards to frequency of injections, it’s been really interesting and frankly one of the benefits of running the PrevU program to get real world experience. Obviously, there’s two camps. There’s some that are saying, listen, I care less about extending the duration of the treatment effect and more about making sure that, within that 12-week gap between retreatments, that they get as much benefit as possible. So we have some that we’ve talked to who said, listen, most of the patients that I treat, they’re a center of excellence, they drive and come a long way. They don’t want to have any downtime. So if I can keep them on a 12-week reinjection cycle and I can give them more good days and avoid some of the roller coaster effects that they experienced today, that’s a huge win.

We have others that say, hey, you know what, I’m going to start them on this, bring them back at 12 weeks, but if I see and I can get them to 14 or 16, that’s a huge win. And so, it’s been interesting in therapeutics, I think, because it’s a reimbursed space, because these are debilitating conditions, I think there’s a little bit more of a shift towards, first, I want just get more better days. And then if it turns out that I can extend the duration profile, even better. But we feel based on what we’re hearing from them, it’ll be a big win if we can just do a better job of controlling symptoms within that 12-week current timeframe. In terms of the technique, yes, the same injection technique. And what’s been really encouraging for us is, across a range of different doses, we are seeing that we’re maintaining a very good safety profile, consistent with what we saw in the ASPEN program.

And we think a little bit of that speaks to the peptide formulation and the precision of the product. And so, we continue to be cautiously optimistic that we’re going to see the benefit of this duration profile with, again, a very good safety profile going forward. Last question you asked just about spontaneous use. What’s interesting on the commercial coverage side of it is they ultimately determine kind of what they cover. And we have some of these commercial plans that are covering DAXXIFY as sort of a toxin generically across. And I think from that – from payer to payer, they will ultimately decide with their coverage universe how they are willing to reimburse the product. And so, obviously, we can only promote it for cervical dystonia, but if you look at the payer coverage universe, we do have coverage beyond just cervical dystonia in many of the commercial payer plans.

Operator: The next question comes from Chris Shibutani with Goldman Sachs.

Chris Shibutani: A question on aesthetics and a question on the therapeutic side. Within the aesthetics market, there’s been commentary about the tone of the market overall on fillers as being one that has been a little bit slower to recover or has been lagging somewhat. Can you comment in terms of what you’re seeing and, in particular, with regard to whether you feel as if there is any aspect of filler fatigue in relation to toxins, just observations about the market? On the therapeutic side, appreciate the commentary that you gave about your launch approaches. You’ve talked about account numbers on the aesthetics. Can you help us, as you expand from PrevU to a broader launch, what kind of numbers of accounts you’re talking about here, so that we can hopefully get a sense for gauging progress?

I couldn’t help but notice that you used specifically in your vocabulary when you’re talking about payers that you were trying to put in place a smooth switch process. Is that the focus of the strategy versus say new patient starts?

Mark Foley: On the aesthetic side of it, in terms of what’s impacting sort of the filler market and why was there observed softness in Q1, it’s really hard to tell because it’s one quarter. Obviously, some of the larger players have reported already and noticed a similar observation in Q1. I don’t know if it’s an economic issue where some patients maybe are saying, hey, rather than three syringes, I’m going to get two syringes. We’ve heard some of that. Or whether it’s, like you said, a filler fatigue where people are changing sort of kind of ultimately what they want. It feels like it’s more of a single quarter effect because, if we look at sort of Q2, and again, I know it’s early, it does feel like things are returning a little bit to the normal, I do think we had the post Zoom effect where we saw a little bit of an artificial increase in filler volume after the whole COVID lockdown, being on Zoom for a while, people with a little bit more discretionary spend.

And so, I think that drove a little bit more of an elevated market. I think we’re now returning more to normal. I’ve not heard from clinicians any sort of change in consumer sentiment about filler. So I think it probably had more to do with a little bit of the economics, but that seems to be abating as we move into Q2 and move to the back part of the year. On the PrevU side of it, in terms of the number of accounts, we said that the top 500 accounts, there’s caught on average two injectors per account, top 1000 injectors do about 70% of the volume. So it’s a much more concentrated market. We have a commercial organization of about 20 people that will be targeting this. And that’s a mix of sales reps, market access and medical affairs. And so, we think that’s going to be a pretty good balance.