ProQR Therapeutics N.V. (PRQR): Jennison Associates Grabbed A Large Chunk Of This Biotech Stock

Securities and Exchange Commission

Washington, D.C. 20549

Schedule 13G

Under the Securities Exchange Act of 1934

(Amendment No. 0)*

March 31, 2016
(Date of event which requires filing of this statement)

Check the appropriate box to designate the rule pursuant to which

this schedule is filed:

(X) Rule 13d-1(b)

( ) Rule 13d-1(c)

( ) Rule 13d-1(d)

Name of Issuer: ProQR Therapeutics N.V.

Title of Class of Securities: Ordinary Shares

CUSIP Number: N71542109

*The remainder of this cover page shall be filled out for a

reporting person’s initial filing on this form with respect to

the subject class of securities, and for any subsequent

amendment containing information which would alter the

disclosures provided in a prior cover page.

The information required in the remainder of this cover page

shall not be deemed to be “filed” for the purpose of Section 18

of the Securities Exchange Act of 1934 (“Act”) or otherwise

subject to the liabilities of that section of the Act but shall

be subject to all other provisions of the Act (however, see the

Notes).