Market Movers Today: Solid Biosciences Inc (SLDB), Adaptimmune Therapeutics PLC – ADR (ADAP), Snap Inc (SNAP), Image Sensing Systems, Inc. (ISNS), and More

Solid Biosciences Inc (NASDAQ:SLDB) (The Motley Fool)
What happened: Shares of Solid Biosciences Inc. (NASDAQ:SLDB), a start-up biotech developing a gene therapy for the treatment of Duchenne muscular dystrophy, were down 63.2% as of 9:57 EDT on Thursday. The first patient dosed with the company’s lead candidate suffered a severe reaction that prompted the Food and Drug Administration to place a hold on all studies with SGT-001 until regulators are convinced that it’s safe to continue.

Adaptimmune Therapeutics PLC – ADR (NASDAQ:ADAP) (MarketWatch)
Shares of Adaptimmune Therapeutics Plc ADAP, +24.86% surged 26% Thursday, after the company reported positive early results for a cancer treatment. Adaptimmune is a developer of T-cell therapy to treat cancer and reported three partial responses and one stable disease in the first four patients to be dosed with its with NY-ESO SPEAR T-cells in a second solid tumor: myxoid/ round cell liposarcoma (MRCLS). The patients tolerated the treatment well and GlaxoSmithKline plc GSK, +0.17% has exercised its option to license and commercialize the therapy.

Bloomua/Shutterstock.com

Snap Inc (NYSE:SNAP) (CNBC)
Shares of Snap plunged as much as 5 percent to session lows on Thursday after Rihanna instructed her 60.9 million Instagram followers to delete the app. It’s the second time in a month an A-lister has done some serious damage to Snap’s market capitalization. Earlier this week, Snapchat users began to notice an ad featuring 30-year-old pop icon Rihanna and her former boyfriend, Chris Brown, for the game, “Would You Rather?” The ad, which asks users to choose between slapping Rihanna or punching Chris Brown, seems to reference — and make light of — the couple’s infamously abusive relationship.

Image Sensing Systems, Inc. (NASDAQ:ISNS) (Benzinga)
Image Sensing Systems, Inc. shares climbed 32.6 percent to $4.178. Image Sensing reported Q4 earnings of $0.13 per share on revenue of $4.34 million. The company announced resignation of CFO Richard Ehrich.