Market Movers Today: Iovance Biotherapeutics Inc (IOVA), Key Technology, Inc. (KTEC), Union Pacific Corporation (UNP), and More

Iovance Biotherapeutics Inc (NASDAQ:IOVA) (The Motley Fool)
What happened: Shares of pre-revenue biopharma Iovance Biotherapeutics (NASDAQ:IOVA) rose nearly 30% today after the company announced preliminary results from two phase 2 trials evaluating one of its lead drug candidates as a potential treatment for head and neck and cervical cancers. Management also took advantage of the soaring stock price to announce a share offering that will provide gross proceeds of $172.5 million if all options are exercised.

Key Technology, Inc. (NASDAQ:KTEC) (Benzinga)
Key Technology, Inc. shares surged 49.8 percent to $26.65 as Duravant announced plans to purchase Key Technology at $26.75 per share in cash.

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Union Pacific Corporation (NYSE:UNP) (Seeking Alpha)
Union Pacific (NYSE:UNP) is sharply lower in early trading after missing Q4 EPS estimates by just a penny. The company’s operating revenue of $5.45B edged past the consensus estimate of $5.43B on strength in the industrial products and chemicals commodity groups. The operating ratio was 58.7% of sales for the quarter vs. 62.2% a year ago. CEU update: “We are optimistic the economy will favor a number of our market segments leading to another year of positive volume growth. Increased unit volume, combined with inflation plus core pricing and G55-0 productivity initiatives, should result in another year of revenue growth and improved margins.”

Varian Medical Systems, Inc. (NYSE:VAR) (CNA Finance)
Varian Medical Systems, Inc. (NYSE:VAR) is having an incredibly strong start to the trading session this morning, and for good reason. The company has announced that it reached a key agreement surrounding the sale of a key medical product. Of course, this led to excitement among investors, sending the stock screaming for the top. Today, we’ll talk about the news, what we’re seeing from VAR, and what we’ll be watching for ahead.

Summit Therapeutics PLC (ADR) (NASDAQ:SMMT) (Benzinga)
Summit Therapeutics PLC (ADR) shares gained 18 percent to $14.41 after the company disclosed that ezutromisd significantly reduced muscle damage in DMD patients in 24-week interim data.

Ford Motor Company (NYSE:F) (CNBC)
Ford reported adjusted quarterly profit of 39 cents per share, falling 3 cents a share short of estimates. Revenue also beat forecasts. Ford said North America was its only profitable region last quarter, with overall results hurt by rising commodity costs and unfavorable currency exchange rates.

American Airlines Group Inc (NASDAQ:AAL) (MarketWatch)
Shares of American Airlines Group Inc. AAL, -3.08% gained a little more than 1% before turning down in premarket trade on Thursday after the company reported fourth-quarter earnings that were above Wall Street expectations. American Airlines reported net income of $258 million, or 54 cents per share, compared with $289 million, or 56 cents per share during the same period a year ago. Excluding special items, earnings per share were 95 cents, above FactSet’s consensus for 92 cents.

Horizon Global Corp (NYSE:HZN) (The Motley Fool)
What happened: Shares of branded towing and trailer company Horizon Global Corp (NYSE:HZN) plunged as much as 29.2% in trading Thursday after lowering its full-year 2017 guidance. At 12:50 p.m. EST shares were still down 27.1% on the day. So what: Revenue is now expected to grow between 37.2% and 37.6% in full-year 2017 versus previous guidance of 38% to 41%.

Newell Brands Inc (NYSE:NWL) (Proactiveinvestors.co.uk)
Consumer goods group Newell Brands Inc (NYSE:NWL) saw shares tank in New York as it emerged that it was mulling strategic options for the group, which could see its customer base cut in half. It also lowered its full year guidance, now expecting sales growth of 0.8% against a previous forecast of 1.5% to 2% Shares slumped over 18% to US$25.26. The firm, whose brands include Rubbermaid, will also explore options for some of its industrial and commercial assets, as well as reduce its factory and warehouse footprint fall by 50%, it said.