Market Movers Today: Iovance Biotherapeutics Inc (IOVA), Key Technology, Inc. (KTEC), Union Pacific Corporation (UNP), and More

Summit Therapeutics PLC (ADR) (NASDAQ:SMMT) (Benzinga)
Summit Therapeutics PLC (ADR) shares gained 18 percent to $14.41 after the company disclosed that ezutromisd significantly reduced muscle damage in DMD patients in 24-week interim data.

Ford Motor Company (NYSE:F) (CNBC)
Ford reported adjusted quarterly profit of 39 cents per share, falling 3 cents a share short of estimates. Revenue also beat forecasts. Ford said North America was its only profitable region last quarter, with overall results hurt by rising commodity costs and unfavorable currency exchange rates.

American Airlines Group Inc (NASDAQ:AAL) (MarketWatch)
Shares of American Airlines Group Inc. AAL, -3.08% gained a little more than 1% before turning down in premarket trade on Thursday after the company reported fourth-quarter earnings that were above Wall Street expectations. American Airlines reported net income of $258 million, or 54 cents per share, compared with $289 million, or 56 cents per share during the same period a year ago. Excluding special items, earnings per share were 95 cents, above FactSet’s consensus for 92 cents.

Horizon Global Corp (NYSE:HZN) (The Motley Fool)
What happened: Shares of branded towing and trailer company Horizon Global Corp (NYSE:HZN) plunged as much as 29.2% in trading Thursday after lowering its full-year 2017 guidance. At 12:50 p.m. EST shares were still down 27.1% on the day. So what: Revenue is now expected to grow between 37.2% and 37.6% in full-year 2017 versus previous guidance of 38% to 41%.

Newell Brands Inc (NYSE:NWL) (Proactiveinvestors.co.uk)
Consumer goods group Newell Brands Inc (NYSE:NWL) saw shares tank in New York as it emerged that it was mulling strategic options for the group, which could see its customer base cut in half. It also lowered its full year guidance, now expecting sales growth of 0.8% against a previous forecast of 1.5% to 2% Shares slumped over 18% to US$25.26. The firm, whose brands include Rubbermaid, will also explore options for some of its industrial and commercial assets, as well as reduce its factory and warehouse footprint fall by 50%, it said.