We don’t have to wait for some specific number. While once we have a critical number of patients involved in each of these, we’ll be able to submit interim data for peer review. And so by — it’s a little bit hard to know until we have a little bit better trajectory on the projections here, but certainly by midyear, I would expect that we would have some of the, particularly, the retrospective and the CYFT data submitted and — for peer review and published. The other one may be a little bit more time. But right now with online journals, turnaround time for peer review is not kind of big issue. So these are just ballpark numbers, ballpark targets, where we look to end up and hopefully that makes sense.
Mark Massaro: Yeah. So, yeah, so MolDX is likely looking for approximately 200 individuals in a prospective observational study?
Dr. Lishan Aklog: I think that’s about right. We have right now targeted 400 patients in the true prospective studies that concluded in the listed registry. We certainly will be able to combine those. But you’re right, because if you think about it, our positivity rate is about 7% to 10% and that’s where you need the numbers, right? So if you have 400 patients, let’s say, at a 10% positivity rate, that means there will be 40 patients who are positive and you could show that those 40 patients did not get referred for — that they did get referred for endoscopy. And then the — obviously, the other 160 patients, that’s pretty large number to demonstrate that negatives or not, sorry, not 160, 360 patients that show that the negatives are not getting referred for positive.
Mark Massaro: All right. Perfect. Yeah. Thanks for clarifying that the physician just needs to order it rather than the patient needs to complete the procedure.
Dr. Lishan Aklog: Yeah.
Mark Massaro: Cool. All right. So my next question, the San Antonio Fire Department is really, really interesting, because that’s about one-fourth of your volumes in Q1 based on my math. And I think you noted in the press release that firefighters have a higher risk for GERD and esophageal cancer. So and I think you indicated that your near-term pipeline for future events is robust. I would love to hear just a little bit more about maybe what some of the other high risk groups are, what your funnel looks like and how many of these do you think you might be able to pull off in 2023.
Dr. Lishan Aklog: Great. So the pipeline is robust. We have — obviously, you’re going to focus on your successes first. So the initial focus has been on other fire departments. And as you mentioned, the key lynch men there is that is the published well-established data of a 65% increase risk of esophageal cancer in firefighters based presumably on environmental exposure. So there are a lot of firefighters who have fire departments. We’re picking up the phone and calling a lot of them, and we expect to start seeing more on those sites. But then as I mentioned, Mark, this sort of folds into kind of the broader — there are certainly other higher risk groups. You can think of other unions, truck drivers, other placement and other public service groups.