Matt Miksic: So, I had just one on — a follow-up on guidance. Joe, if you could talk a little bit about following up on some of the conservatism and maybe the bright spots, the China assumptions that you’ve made for procedure disruption and maybe VBP, if you could give us a sense of how long into €˜23, you expect that to go? And then what you assume for the STELARA LOE? And then, on this sort of conservative side on the bright spot, I think you just kind of covered, I guess, the ortho trends. I understand you aim at this mid-single-digit range for performance, but you had a very, very strong back half in the U.S. And I’m just wondering does that kind of strength in ortho and the spine, for example, which is kind of well above sort of historical ranges. Does that kind of continue into €˜23, or are we assuming that we went into in some comp challenges there, or how — what sort of elements are contemplated in your guidance, that would be helpful?
Joe Wolk: First of all, I guess let me follow up to Terence’s question with respect to how he positioned, conservatism. I probably did miss an opportunity to speak about some of the things that maybe could go better on our behalf. And some of that could be a quicker rebound in China, whether that be in both MedTech or Pharmaceuticals. Right now, we’re assuming there is some carryover effect from the COVID surges we saw in the fourth quarter. The teams on the ground seem to indicate that it’s still persistent, but if that rebounded a little bit quicker. I think also looking at the multiple myeloma portfolio, and the performance of CARVYKTI or TECVAYLI could be significant and opportunities or pockets for upside. We’re obviously excited by the Abiomed acquisition and what that could possibly mean.
And bringing the capabilities of Johnson & Johnson, both in terms of scale and reach, presents some opportunity that maybe isn’t in the current projections. So, there are some opportunities for outperformance. Right now, we like where the number is at with respect to that. China and VBP specifically, I would say that is a dynamic that’s not really a new phenomenon for us. We had won a number of tenders at the end of 2021 that were persistent throughout 2022, and we continue to win tenders. And we think over time that the volume and the opportunity to help many more patients will be persistent with that. So, we are — it’s part of the guidance that we see today that we’ve offered today, but it’s not really much more pronounced in terms of the impact it has on the business versus what we’ve experienced already.
Operator: Next question today is coming from Trong Win from Credit Suisse.
Unidentified Analyst: Just a question on STELARA erosion expectations. So, I was hoping you can give us some thoughts about the cadence of biosimilar products that are going to be coming along this year. None are approved yet. But, can we expect the first company to enter with exclusivity for six months, something we’ve seen with HUMIRA, and then the rest coming in 2’4? Or should we expect all the players to come at once? So, any color on this patent answer would be helpful. Thanks.
