Operator: Please standby for our next question. Our next question comes from Jessica Fye with JPMorgan. Your line is open.
Jessica Fye: Great. Good evening, guys. Thanks for taking my questions. Does the IRA influence your business development priorities or how you evaluate potential targets? And what about within your own pipeline? Does it impact your thinking on which indications or efforts to prioritize?
Bruce Cozadd: So, I guess, I would say, like other companies in our industry, we’re continuing to evaluate the impact of the IRA legislation, particularly as we learn more over time about how it’s going to be implemented to see how that will impact our investment decisions, and it may impact our investment decisions across our R& D portfolio, but also importantly, across corporate development opportunities. here are parts of IRA we liked, including really trying to address out-of-pocket cost for patients. I think that was a step in the right direction. There are other provisions that we think are actually challenging to innovators in terms of some of the probably unintended consequences or not fully recognized consequences in terms of providing a return on capital for those investments.
So we, like everyone, will be looking at potential impacts. I don’t think we believe for our existing commercial portfolio of products. We see much certainly in any near-term period that would concern us, but we will take it into account when we’re making longer-term investment decisions.
Jessica Fye: Thank you.
Operator: Our next question comes from Jason Gerberry with Bank of America. Your line is now open.
Jason Gerberry: Hey, guys. Thanks for taking my question. First question, not asking for guidance, but just curious if directionally you see 2023 as a revenue growth year? And the reason I ask is because you have this 2025 target out there. And I think from an investor standpoint, it’s easier to believe that if you think 2023 is a growth year. And given the generic competitor entry, I think it would just be something that would be helpful to you guys could address at some threshold. And then the Epidiolex quarter was impressive. I’m just curious if you can speak a little bit to like the one or two biggest growth drivers on a year-over-year basis. You guys were pushing into adults, into rural and suburban kind of areas. So just kind of curious if you could give us a little bit more color on what specifically were some of the bigger growth drivers for Epidiolex? Thanks.
Bruce Cozadd: Maybe I’ll ask Renée to take the broader revenue trends question, and I hear that you’re not asking for guidance, so thank you. and then maybe I can turn it over to Dan and Kim to talk a little bit about our Epidiolex growth.
Renée Galá: Yes. Thanks, Bruce. And Jason, thanks for the question. So with respect to 2023, as you would expect, we typically provide that full year guidance for a new year alongside our full year results in the first quarter. So you can expect that from us in early 2023. However, with respect to how we’re thinking about 2023 relative to AGs or potential competition, I would say we continue to expect Xywav to be the oxybate therapy of choice. We’re confident in the path that we have ahead of us for 2025 and the ability of the oxybate franchise, more broadly, to deliver $2 billion of revenue across Xywav, branded Xyrem and then the royalties of AGs, which, of course, carry meaningful economics to us. But going back to 2023 and Xywav, as you would have listened to our comments and looked at our third quarter results, we believe we are very well positioned for Xywav to be the therapy of choice within the oxybate for the year.
