Is Rezolute, Inc. (RZLT) the Best Multibagger Stock to Buy Heading into 2025?

We recently published a list of 10 Best Multibagger Stocks To Buy Heading into 2025. In this article, we are going to take a look at where Rezolute, Inc. (NASDAQ:RZLT) stands against other best multibagger stocks.

November has been an eventful month so far for the market as the Fed cut rates by a quarter percentage and president-elect, Donald Trump won the election for the second time. The market reacted positively to these events as the major indices touched all-time highs and even Bitcoin finally broke off its shell after many months, reaching an all-time high of $93,000.

More recently, Federal Reserve Chair Jerome Powell stated that solid economic growth, low unemployment, and inflation above 2% mean there’s no urgency to cut interest rates. Speaking in Dallas, Powell said inflation is on a path toward the Fed’s 2% target, allowing for cautious policy adjustments.

He highlighted the economy’s strong fundamentals but acknowledged persistent inflation pressures. While a rate cut is expected by the market in December, it anticipates fewer cuts next year due to steady inflation and policy uncertainties. According to the CME FedWatch, 62.4% of the interest rate traders expect a 25 bps rate cut in December. However, in January, 55.5% of the market anticipates the rates to remain the same after the December cut.

Powell emphasized that the Fed will monitor inflation closely, especially housing costs, as it aims to reach its target sustainably.

READ ALSO: 12 High Growth Large Cap Stocks to Buy Now and 10 Best Low Volatility Stocks to Invest in Now.

Election Boosts Market Optimism but Risks Remain

Stuart Kaiser, Citi’s head of equity trading strategy recently joined CNBC’s Closing Bell. In the post-election discussion, Kaiser expressed a generally optimistic outlook, with confidence that the markets have cleared the immediate uncertainties related to the election. Kaiser noted a temporary boost from this event but emphasized that moving forward, market focus will return to U.S. economic growth, the Fed’s actions, and corporate earnings.

While he believes valuations are currently more justifiable with expected growth from deregulation and new policy changes, he remains cautious about risks tied to bond market movements and rising yields. He suggested that rising yields linked to economic growth are manageable for equities, but warned against yields climbing due to fiscal or tariff issues, which could unsettle the market.

Regarding equity strategy, Kaiser advocated a cautious approach to small-cap investments, preferring high-quality, profitable small caps due to their domestic focus, which could shield them from trade policy risks impacting larger companies. Additionally, although Kaiser doesn’t handle non-traditional assets directly, he acknowledged that assets like Bitcoin might gain traction in a strong economic or supportive policy environment.

A scientist observing a microscope in a cutting edge biotechnology laboratory.

Our Methodology

For this article, we used the Finviz stock screener to identify over 350 stocks with share price gains of over 100% in the last 12 months, as of November 13. Next, we narrowed our list to 28 stocks with share price gains of 200% either in the last 12 or 24 months and Buy or better ratings from analysts. From that list, we removed the stocks that had negative share price returns compared to 24 months ago and finally narrowed the list to 10 stocks with an average analyst price target upside of over 100%. The 10 best multi-bagger stocks are listed in ascending order of their average price target upside.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 275% since May 2014, beating its benchmark by 150 percentage points (see more details here).

Rezolute, Inc. (NASDAQ:RZLT)

1-Year Share Price Performance: ~573%

2-Year Share Price Performance: ~265%

Average Price Target Upside: 126.48%

Rezolute, Inc. (NASDAQ:RZLT) is a late-stage rare disease company focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Its lead clinical asset, ersodetug, is an intravenous human monoclonal antibody designed to treat hypoglycemia caused by various forms of HI. The antibody works by binding to a unique site on the insulin receptor, reducing insulin’s effect and helping restore glucose balance.

Rezolute (NASDAQ:RZLT) provided fiscal Q1 2025 results and business updates on November 7. The company’s focus for 2025 will be on advancing its Phase 3 programs for congenital and tumor hypoglycemia (HI) patients. CEO Nevan Elam highlighted the progress made in enrolling patients for the sunRIZE trial, a global Phase 3 study for ersodetug in congenital HI, and the upcoming U.S. enrollment expected in early 2025.

Topline results for the congenital HI study are expected in the second half of 2025. For tumor HI, the Phase 3 study is progressing with enrollment expected in 2025, and topline results anticipated in 2026.

As of September 30, 2024, Rezolute (NASDAQ:RZLT) reported $117.8 million in cash, cash equivalents, and marketable securities, down from $127.1 million on June 30, 2024. On November 8, The Fly reported that JMP Securities analyst Jason Butler increased the price target for the company to $8 from $7 while maintaining an Outperform rating on the stock after the company’s Q1 results.

The analyst noted that the Phase 3 trial for ersodetug in congenital hyperinsulinism is progressing with patient enrollment, and the results are expected to be released in the second half of 2025.

Overall, RZLT ranks 6th on our list of  best multibagger stocks to buy heading into 2025. While we acknowledge the potential of RZLT as an investment, our conviction lies in the belief that AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. If you are looking for an AI stock that is more promising than RZLT but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.

READ NEXT: 8 Best Wide Moat Stocks to Buy Now and 30 Most Important AI Stocks According to BlackRock.

Disclosure: None. This article is originally published at Insider Monkey.