We recently compiled a list of the Jeff Bezos Investments in 2025: 12 Companies Bezos Is Investing In. In this article, we are going to take a look at where GRAIL, Inc. (NASDAQ:GRAL) stands against the other companies Bezos is investing in.
Since leaving his position as CEO of Amazon in 2021, Jeff Bezos has been quite active. He has been investing in real estate and companies, staying involved with Amazon and Blue Origin, and becoming close to President-elect Trump. “I’ve actually never worked harder,” he told the New York Times last December.
Jeff Bezos has directly invested in at least 108 startups across all industries since 1998, when he was reported to have invested $250,000 into Google. Although he does not publish his returns nor do the firms in which he invests, he has made early bets on several companies that have gone on to launch some of the most high-profile tech IPOs in the recent decade.
He certainly has enough cash to play with. According to Forbes, Bezos has sold around $32 billion in his main company shares since its initial public offering, including nearly $14 billion last year. He is now the third richest person in the world, with a net worth of $237 billion.
Although Bezos has spent a lot of time and money on yachts, aircraft, and real estate since transitioning from CEO to chairman of Amazon in 2021, he remains actively involved in his venture portfolio, advising portfolio firms and assisting with investment selections. However, Bezos isn’t as engaged as, say, a typical large venture capital firm: he was only the lead investor in one funding round last year (for Swiss-Mile), which means he likely didn’t acquire significant stakes in the majority of the companies, and he isn’t known to hold a board seat at any of the startups he has backed.
Two of the companies Forbes contacted said that a Bezos spokesman asked them not to discuss with the media about the Bezos investment, but those who did speak favorably about it. Swiss-Mile’s Bjelonic, Chief Executive Officer & Co-Founder, made the following comment:
“What I was most surprised with was actually how well he understood the technology behind the Al training. He would ask questions about reinforcement learning, imitation learning, how it works, going all the way to the details of the physics elements that are needed on our side.”
Regardless of how invested Bezos is in any given company, publicizing his name as an investor provides marketing exposure.
The autonomous robot business is still in its early stages of commercialization. Bjelonic compared the business to a “blue ocean,” predicting that in ten years, hundreds of robotics startups will fail while only a few will flourish. It will take years to determine whether those bets pay off.
However, the chances may be in Bezos’ favor, in part because he can combine his economic expertise with the fact that he will almost certainly be able to invest in any firm he chooses.
According to Columbia Business School professor Michael Ewens, the “best” and “hottest” startups reach out to people like Bezos first.
“In general, he’s a very good investor, because he’s getting calls. He’s first in line.”
A biotechnologist in a lab wearing an apron and safety glasses, working on a biopharmaceutical process.
Methodology
We examined the investments of Bezos Expeditions, Jeff Bezos’ family office, to identify key companies he’s invested in. All selected firms are publicly traded except the last one, and the stocks are ranked in ascending order using Insider Monkey’s database of over 1,000 hedge funds in Q4 2024 to gauge hedge fund sentiment for stocks. The portfolio also includes one of his most recent private company investments, which is ranked last on our list.
Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 373.4% since May 2014, beating its benchmark by 218 percentage points (see more details here).
GRAIL, Inc. (NASDAQ:GRAL)
Number of Hedge Fund Investors: 28
Market Capitalization as of February 24: $1.54 billion
GRAIL, Inc. (NASDAQ:GRAL) is a biotechnology company focusing on developing the next generation of cancer diagnostic tools that will help doctors identify dangers early on and maybe prevent lethal diseases from causing damage, making it a promising treatment. It was originally developed within Illumina, spun off in 2016, reacquired in 2021, and eventually divested again in 2024 following a dispute with European regulators. Still, shares are up, and Bezos Expeditions has been on board, with the business maintaining a large stake in the company and being included in Jeff Bezos Stock Portfolio.
GRAIL, Inc. (NASDAQ:GRAL) reported a significant growth in Galleri revenue in the United States, which climbed by 45% YoY to over 137,000 Galleri tests sold. Fourth-quarter 2024 revenue surged by 26% to $38.3 million, contributing to full-year revenue of $125.6 million, a 35% increase over 2023. The company improved cost efficiency by introducing a new Galleri test version, cutting sequencing costs, automating procedures, and expanding lab capacity. Strategic collaborations with Quest Diagnostics made test ordering simpler, while TRICARE approval increased coverage for some patients. The net loss improved by 48% in Q4, and cash burn is anticipated to drop by more than 40% by 2025.
Its stock has shot up by more than 127% in 2025. GRAIL, Inc. (NASDAQ:GRAL) declared sales of $124-126 million for 2024, above estimates, and reported 137,000 tests sold, up from 94,000 in 2023. Larry Ellison, Oracle’s Chief Technology Officer and former CEO, remarks on the use of blood tests for cancer vaccinations, as well as the partnership with Quest Diagnostics, which provides access to over 500,000 providers, has strengthened the trust of investors.
Overall GRAL ranks 8th on our list of Jeff Bezos’ investments in 2025. While we acknowledge the potential for GRAL as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter timeframe. If you are looking for an AI stock that is more promising than GRAL but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.
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Disclosure: None. This article is originally published at Insider Monkey.
