Inotek Pharmaceuticals Corp (ITEK): Billionaire Ken Griffin’ Citadel Investment Group Raises Stake to 6.5%

Page 2 of 10 – SEC Filing

1.	NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Citadel Advisors LLC
2.	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (a) ¨ (b)¨
3.	SEC USE ONLY
4.	CITIZENSHIP OR PLACE OF ORGANIZATION Delaware

NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH	5.	SOLE VOTING POWER 0
	6.	SHARED VOTING POWER   1,871,258 shares
	7.	SOLE DISPOSITIVE POWER 0
	8.	SHARED DISPOSITIVE POWER See Row 6 above

9.	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON See Row 6 above
10.	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ¨
11.	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 6.5%1
12.	TYPE OF REPORTING PERSON IA; OO; HC

1

The percentages reported in this Schedule 13G are based upon 28,801,988 shares of common stock outstanding (composed of (i) 26,930,730 shares of common stock outstanding as of August 9, 2016 (according to the Form 10 Q filed by the issuer with the Securities and Exchange Commission on August 10, 2016) and (ii) approximately 1,871,258 shares issuable upon the conversion of certain convertible notes held by the Reporting Persons and certain of their affiliates).