So you will see that balance out over time. We don’t have any doubts on that. And then, on the X, I want to reemphasize, and I think you will have seen this from your channel checks as well, demand and interest in the innovation and the capabilities that the X brings remain strong. I think we are very excited about the launch of the 25B and I think those of you who attended ASHE would have seen our customers’ interest in that and the data that’s coming out of the other 25B and the improvements that we continue to make on the software really resonate with our customers. So we remain very interested in that.
Operator: And our next question will come from Puneet Souda with Leerink Partners.
Puneet Souda: Yeah, hi, Jacob. Good to have you on board here. So if I could ask two-part questions, with the 25B launch, can you talk a little bit about how, and maybe Joydeep can chime in and talk about how the transformation is going to be sort of over the next couple of months. You obviously get a price uptick with the 25B, but not all customers are going to be able to essentially fill up that flow cell. So there’s going to be a bit of an ebb and flow. So maybe if you could talk a little bit about that, at least qualitatively in the near term. And then a bigger competition question. Jacob, you’ve seen the LCMS businesses and other businesses in China, what do you imagine for China — for Illumina with, one of the bigger competitors over there?
How do you see Illumina’s position in China, longer term? And if I may just ask, again, on competition, one of your diagnostic customers, NIPT and MRD customer pointed out that they’re validating different platforms. So again, what’s your view on competition? Thank you.
Jacob Thaysen: No, thank you very much, Puneet and again, I’m very pleased to be here. Let me start with the China question. As you’re right, I have certainly some experience of running businesses in China. I’m very familiar with the China itself and how to operate businesses there. So what is, of course, more unique for Illumina than some of the other life science tools companies is that Illumina has a Chinese competitor that have at least good enough sequencing capabilities here. But China continues to be an extremely important country for us and we are right now working through and in China for China strategy to really be much better positioned in China going forward and we are committing to China and I think we can actually do really well in China.
Many of our customers in China prefers to work with Illumina for what we stand for, both quality, but also that we are the number one brand out there. So we will continue to be very strong in China. Generally speaking on competition, yes, you’re right. There are competition out there. As you also know, I’m very familiar with being in a very competitive environment and I think that with what Illumina has which I think will serve us extremely well is that we have a very strong brand. We have a very strong installed base. Almost all papers coming out is based on our technology and also, of course, what I see internally with the roadmap we have for the pipeline of new products coming out, our innovation capabilities, will continue to position us very extremely competitive in this environment.
But of course, I understand and I’m fully aware that we will be in a very competitive situation forward. And in the end, I think that just keeps us really focused on our customers and we’ll do our best for our customers. So I’m here, I’m ready to fight for it.
Joydeep Goswami: Yeah, maybe I’ll tag on there. Let me start with the competition. We obviously, as Jacob said, take it seriously, but also monitor it very carefully across the globe through what we’re seeing out in the field. So I will say outside of China, we have seen the competition and share have been what we had expected. Obviously, with new market entrants, you will see a little bit of a decline in share, but it has been outside of China very much according to expectations. On the 25B, Puneet, so let me start by saying what we have seen in this is early indicators that when we look at sequencing activity growth and we measured it by gigabase, we are seeing that customers who have adopted DX have seen a faster growth rate in output and sequencing output than customers who have not adopted DX, right.
So this is an encouraging sign that X is actually spurring more sequencing activity at these customers. And again, it’s still very early days. They’re ramping up, they’re validating fully on their particular workflows. With 25B, I think you’re right. It will spur even more capacity and experiments. We’ve heard customers that want to run very large single cell experiments, for example, be very excited about this 25B and the capabilities that it brings. So we expect that to play out. I think when you get in the dynamics of whether you’re running full flow cells or not, there is a very complex interaction of things that will lead to higher prices per gigabase until you fully load your flow cells. So we can get into that offline, but we do expect those dynamics to be very similar to what you saw when you brought on NovaSeq 6000 and some of the other S4 flow cells, etcetera.
Jacob Thaysen: But I think also, Joydeep, just to finish on the opportunity that we have seen, at least the customers that I’ve met here in the clinical space, are very excited with the new flow cell as this opens up for new assays, new products, offering that they haven’t had before. So while it will take them a little while, of course, to validate and get up and running, we see many of them right now rushing to be first to market with this.
Operator: And our next question will come from Dan Arias with Stifel.
Dan Arias: Yeah, hi guys, thanks for the question here. Jacob, just to follow up on the special committee that will look at GRAIL, what’s the general timeline that they’re expected to be on with respect to reaching a decision and then can you update us on when the GRAIL team is expecting to see a readout for the NHS gallery study at this point, thanks.
