GSK plc (NYSE:GSK) Q4 2023 Earnings Call Transcript

Steve Scala: Thank you. On Cabenuva, emerging resistance and 1% to 2% of people is viewed by clinicians as a real risk seems to occur in the obese population but could tarnish prospects overall. So I’m just wondering what is GSK’s position on this? And secondly, pneumococcal vaccine do you plan an efficacy study? And if not, is that because you think that is not important? Thank you.

Emma Walmsley: Well, we do think the pneumococcal vaccine is very important, so Tony can comment on that. But Deborah, I’m not sure we characterize it quite as Steve has.

Deborah Waterhouse: So you’ve got less than 1% failure on Cabenuva. There are some risk factors that all physicians are aware of and this is one of them being resistant to ropibrine is the other. And then there is a sort of relatively rare subtype, so we can clearly characterizing where people should not use the drug. It’s a very limited population. And the real-world evidence is actually showing less than 1% in fact significant failure because physicians have taken on board the multi-barrier analysis that guides where to use it. And when they use it in that population, you see very low levels of failure and very, very high satisfaction with the drug and continuity on the drug over time. So that’s why we’re seeing significant growth with Cabenuva that we are.

Emma Walmsley: Thanks. Tony?

Tony Wood: Just quickly then on pneumococcal. Obviously, we’re focused on using immunogenicity data in particular restarting the infant 24 this year alongside the data that we have in adult and starting adult 30+. In terms of our strategies with regards to vaccine efficacy and broader competitive content of that, I’ll keep that to future discussions.

Emma Walmsley: Great. So thank you very much everyone for the call. I’m very pleased who have been able to share with the team today GSK is delivering on its commitments strengthening our outlook for growth we are making great progress. We know there’s always more to do and we’re looking forward to keeping you updated. Thanks to everybody for joining the call.