Next, I want to show you a PatientMatch and I will spend the next few slides really diving intoPatientMatch because it is, in many ways, the most complex, innovative, and powerful new features in ICE 2. In addition to all of the patient report information, there is a new section of the report to highlight PatientMatch. Here, PatientMatch is taking our hypothetical case of Dr. Cole and her patient with breast cancer and an EGFR mutation and processed our entire genomic database and identified that in our database, there are 22 other practitioners who have seen similar patients. It gives Dr. Cole the opportunity at a click to ask those other physicians of their experience treating those patients. Dr. Cole clicks on PatientMatch because she is interested in finding out more about this EGFR mutation and what it means for her patient with breast cancer.
If you click on this, the PatientMatch feature is loaded and offers her the opportunity to inquire about any of the genomic findings in that patient report. Dr. Cole clicks on EGFR and PatientMatch identifies all of the physicians who matched that profile. Those physicians are listed here, anonymized to protect their privacy. Then the email is generated automatically on Dr. Cole’s behalf, customized to her particular inquiry. We heard loud and clear from physicians that they are very excited about the possibility of inquiring about other experiences in this manner, but they acknowledge that their time is limited and they do not actually have time to crop this email. As a result, we have created this email that includes all of the pertinent information about their patient and all Dr. Cole has to do is click one button to send this request.
When she clicks and requests, PatientMatch then sends this email, on her behalf, to all of these physicians who matched. If we flip to Dr. Miller’s email box, he will receive this email directly in his day-to-day email browser. It says, “Dear Dennis, I have a patient with breast cancer who had an EGFRL858R alteration identified by Foundation One. I am considering targeting this alteration for the next step in treatment of my patient. Foundation Medicine has identified that you may have seen a similar patient in your practice. Would you take a moment to answer a few simple questions that will help me and other physicians learn from your experience?”
Dr. Miller says, “Yes, I will share my experience.” It is taken directly into Foundation ICE. His matching patient’s report is pulled up in a format that is very familiar to him. Above that patient report, [Emma Potter], his own patient with breast cancer in this EGFR mutation,he is asked four simple questions that allow him to quickly and efficiently share his patient experience.
Dr. Miller is first asked if he treated his patient, [Emma Potter], with a therapy targeting EGFR. He is then asked, “Which therapy targeting EGFR, [Emma Potter] received?” This search block is powered by a drug dictionary in the background that automatically completes as he types. He types an ERL and it completes to erlotinib. It then asks Dr. Miller if his patient is still taking erlotinib, how long this patient was on erlotinib. Finally, what the patient’s best response was in erlotinib.
That is the end of the survey. We kept it short, concise and effective. Again, in consultation with a lot of feedback that we see from physicians. They want to help their colleague. They know there’s another patient on the other side of this request but they also recognized that their time is limited. In making four quick inefficient questions, we have optimized for the responding physician while still delivering critical information for the user who will use that information to make their own treatment decision.
We also recognize, of course, that there’s often other contexts that is required for a clinical case and we therefore give Dr. Miller the opportunity to provide either content information or additional comments or both, but neither is required if Dr. Miller does not have time.
