Operator: The next question is from Trung Huynh from Credit Suisse. Please go ahead.
Trung Huynh: Thanks for squeezing me in. I’m Trung Huynh from Crédit Suisse. Last month the American Academy of Pediatrics released their guidelines to treat childhood obesity. In those guidelines, they recommended a lifestyle intervention obviously, is the core component. But also they said, they would consider treatment with anti-obesity medications. So I thought, what’s your thoughts on anti-obesity medications in children? Is this a scenario that you are moving into or considering moving into? Do you have any trials with children or adolescents? Thank you.
Joe Fletcher: Thanks Trung for the question. Mike over to you again comment on these recent guidelines that were put out.
Mike Mason: Yes. Thanks. I mean this is a significant unmet need. Back to the question that we asked earlier about the Treat Reduce Obesity Act. We need to prove the health of America. We have too many people who live with obesity in the US and that includes unfortunately adolescents and feeds. So, I think they took the right action in order to really identify this as an issue that healthcare professionals do need to pay close attention to. We obviously always advocate for diet and exercise is the first approach of this. But if that’s not successful then you really only option at that point is medication treatment. We do think it’s important and responsible for us to test the appetite in feed and adolescents and we have activity ongoing to do that.
Joe Fletcher: Thanks Mike and thanks Trung for the question. Lois, next question.
Operator: The next question is from Carter Gould from Barclays. Please go ahead.
Carter Gould: Great. Thank you for taking the question. I guess one for Anat. Back in December, you highlighted austerity measures in Europe as a potential risk. At that time that was a bit of a unique position. We hadn’t heard that from many companies since that time. We’ve heard kind of similar messaging from some but not all. And apologies if I missed it I don’t think I heard anything today on this front. So, I know it’s only been sort of 45 days or so since you made those comments, but any advances in sort of how you’re thinking about this? And any specific products or countries we should think about that impact? Thank you.
Joe Fletcher: Thanks Carter for the question. I’m actually going to hand this over to Ilya Yuffa, who’s our President of Lilly International to comment on the European austerity measures.
Ilya Yuffa: Yes, I appreciate the question. There have been a number of markets in Europe that have taken some austerity measures, partially due to Ukraine crisis and energy crisis and inflation in Europe. We have seen Germany, France, obviously, the UK, voluntary system we think is broken and so we exited that. And so we — there are some austerity measures in there. We’ve contemplated that into our guidance for 2023. And the overall impact is modest relative to historical declines in price in prior years. We expect that to continue to be in that mid-single-digit decline in price in Europe.
Joe Fletcher: Thanks Ilya. Thanks Carter for the question. Lois, next question.
Operator: The next question is from Andrew Baum from Citi. Please go ahead.