Deerfield Management’s Top Health Stocks ~ Auspex Pharmaceuticals Inc (ASPX), Horizon Pharma PLC (HZNP), AbbVie Inc (ABBV)

James Flynn‘s Deerfield Management has filed its 13F with the SEC for the reporting period of March 31, with the investment manager disclosing a public equity portfolio valued at $3.09 billion. The fund primarily invests in the healthcare sector, with 94% of the value of its public equities residing in health stocks, owing to managing partner and CEO Flynn’s background working in and investing in the healthcare sector. That expertise makes Flynn a wise choice to track when it comes to a sector that can be one of the most challenging to understand for investors. Auspex Pharmaceuticals Inc (NASDAQ:ASPX), Horizon Pharma PLC (NASDAQ:HZNP), AbbVie Inc (NYSE:ABBV), and NxStage Medical, Inc. (NASDAQ:NXTM) are among the top healthcare stock picks of Flynn, which we’ll look at in this article.

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Auspex Pharmaceuticals Inc (NASDAQ:ASPX) is the largest healthcare stock pick of Flynn, who owns 4.45 million shares valued at $446.11 million. Teva Pharmaceutical Industries Ltd (ADR) (NYSE:TEVA) announced the completion of its acquisition of Auspex Pharmaceuticals Inc earlier this month for an equity value close to $3.5 billion. Shares of Auspex Pharmaceuticals Inc (NASDAQ:ASPX) grew over 92% in 2015 thanks in part to its acquisition, and a hefty 454% over the past year. Some of the major shareholders of Auspex were Israel Englander‘s Millennium Management, Alpine Associates, and Water Island Capital.

Deerfield Management’s second-largest health investment was in Horizon Pharma PLC (NASDAQ:HZNP), in which it owns 12.79 million shares valued at $332.23 million. The specialty biopharmaceutical company has a market cap of $5.02 billion and its shares currently trade at $32.28. Horizon Pharma completed the acquisition of Horizon Therapeutics Inc (NASDAQ:HPTX) on May 7 with a tender offer for 86% of the outstanding shares of the latter. With this acquisition, Horizon Pharma PLC (NASDAQ:HZNP) added two successful medicines for the treatment of urea cycle disorders, RAVICTI and BUPHENYL, to its portfolio. The biopharmaceutical company reported net sales of $113.1 million during the first quarter of 2015 with a net loss of $19.6 million. Broadfin Capital and Healthcor Management LP are two other health-focused investment firms that hold major positions in Horizon Pharma PLC (NASDAQ:HZNP), which has gained an even-more-impressive 152% year-to-date.

AbbVie Inc (NYSE:ABBV) ranks as the number three long health pick in the public equity portfolio of Deerfield Management through a position of 1.53 million shares valued at $89.80 million. Shares of AbbVie have remained stable throughout the year with growth of 2.38% year-to-date. Consistent with the acquisition spree that has been prevalent in the pharmaceutical industry of late, AbbVie Inc (NYSE:ABBV) announced the acquisition of Pharmacyclics, Inc. (NASDAQ:PCYC) for $21 billion earlier this year. The acquisition is poised to help AbbVie make progress in the fast-growing cancer drug treatment industry and should allow it to offset the effects of its head-on-head collision with Gilead Sciences, Inc. (NASDAQ:GILD) in the HCV drugs market, with the latter now controlling 85% of the HCV drug market with its Sovaldi and Harvoni drugs, which are available for $84,000 and $94,500 for a 12-week standard treatment course. AbbVie Inc launched Viekira Pak in December 2014 to eat-away the market share of Gilead with a price tag of $83,300 for a similar 12-week standard treatment course. Cliff Asness‘ AQR Capital Management, Orbimed Advisors, and Point State Capital are among the primary stockholders of AbbVie Inc.

NxStage Medical, Inc. (NASDAQ:NXTM) is the final top healthcare stock pick of Deerfield Management we’ll look at, with Deerfield owning 5.07 million shares of NxStage Medical valued at $87.76 million. It has been a rough year for the medical device manufacturer in terms of its share price, which has declined 9.22% year-to-date. NxStage Medical, Inc. (NASDAQ:NXTM) has a market cap of $1.04 billion with a 52-week high of $19.63. The medical firm has received an average rating of “Buy” from six brokers with a 1-year price target of $21.00, which represents an upside of 27.03% from its current share price. Tamarack Capital Management, Steve Cohen‘s Point72 Asset Management, and Sectoral Asset Management hold substantial investments in NxStage Medical, Inc. (NASDAQ:NXTM).

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