Joe Burnett: Yes. would say the feedback has been very strong. Most of the patients that have been enrolled — I don’t want to say enrolled so far that have been treated so far have been done in a clinical trial protocol in Europe and this has been focused primarily on tumor patients or really exclusively on tumor patients today. Those cases that have been performed there, the device has performed exceptionally well. We are very, very pleased with the results. And as I said in my statements, we are using this time to sort of prepare additional training and marketing materials because there are some meaningful differences between the products currently on the market and what Prism has to offer. In the United States, we’ve done cases at one center so far in the United States, and we are in the process of installing at multiple additional centers as well.
Similar to some of the things that we’ve talked about in the past, any time you’re bringing a new piece of hardware and software into a hospital today, the sort of delays, which aren’t even delays anymore, they’re becoming expected of getting a new technology approved through IT at a hospital, has just been more complicated than it’s ever been before. And those teams don’t always meet on a weekly basis, sometimes it’s only a monthly basis. So that’s something that’s — the pace of installation has been a little slower than we expect, but it’s not because people are not interested in trying the product. It’s really just going through the hurdles that are a necessary part of getting a new technology into a hospital in 2023.
Frank Takkinen: Okay. And then last one for me. It sounded like at the end of 2022 there in the last couple of weeks of 2022, there were some cancellations or postponements at least to 2023. Any update on those?
Joe Burnett: Yes, I mean I think the biggest drivers of that, I would say, the most substantial ones were in a couple of buckets. The biggest one just being the timing of some of the preclinical services and the way that we recognize revenue. You noticed in Q4, as Danilo mentioned, our cash burn was only $3 million. And part of the contributor to that is some of our pharma partners that are effectively prepaying for services because they do understand the risk and time lines of certain services being ready. We can’t perform a certain test, for example, if we don’t get the drug delivered to us. So what we have asked and been successful in asking is that the pharma partners can provide some of the cash up front. So even if there is a delay, we are not losing our time and energy on it.
From a revenue standpoint, however, that means we don’t always recognize the revenue. And I think that’s some of the — those were the primary delays that we saw in Q4 of last year. And just honestly, it’s going to be a part of normal. The plan that we have is that across 50 different partners and a number of different programs that there will be some delays. However, there’s enough shots on goal in any given quarter that will perform the services to keep the revenue growing. So I think that was one of the primary contributors is — and it’s something that there’s nothing I would say that we lost in 2022 that we don’t expect to regain in 2023. So it really is a timing issue. The other side of the equation is that there were some definite postponements and high cancellation rates, especially around the last few weeks of December, which contributed probably to another $100,000 to $150,000 of case postponements.
