BioAtla, Inc. (NASDAQ:BCAB) Q2 2023 Earnings Call Transcript

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Reni Benjamin: Got it. And I think I’ve asked you this before, but now that you’re dosing the melanoma patients, do you kind of wait to see how this reads out before testing the other indications with this liquid biopsy? Or do you kind of — I think in the past, you may have said that with these other indications, you have quite a robust or to expression. And so we don’t really need to use the assay.

Jay Short: Well – yes, I think rolling it out – we definitely are working at the research level to make sure we have it covered in these other areas, including axle, if we need it. However, to roll it out with the expense that you might want to put behind the companion or need to put behind the companion diagnostic, No, we wouldn’t do that until we got more confirmation beyond what we have at the moment because we’re – keep in mind, we’re also wanting to manage our capital, and we’re forecasting to get into 2025. Well, that means you got to be prudent on how you do things.

Reni Benjamin: Got it. One final one for me. The Phase II investigator-sponsored ovarian study in platinum is an ovarian gas, are you getting the 10 patients. What kind of data do you need to see or you would like to hit so that I don’t know, it would be kind of brought back in-house and developed under a corporate IND versus keeping it as an IST? Or is this something — is this an indication that you would really just like to be seeing developed by somebody else, even if it’s an academic partner?

Jay Short: Well, we’ve had corporate – we’ve had companies ask us about the ovarian cancer. So there’s interest out there. And what the exact cutoff is, is interesting because it depends on how that whole field is emerging a little bit, but I think the bar is fairly low at the moment in terms of what you need to see to advance this. But I think how we’ll take that forward is going to be linked to the data. What that exact cutoff will be is still being debated. But beyond that, it’s hard to answer at this particular second. We have our own – so I mean I would say I’ll just throw out, I think 20% still quite viable if you’re seeing responses in that. Keeping in mind, though, a lot of these drugs get approved on PFS and not ORR.

So I just – we have to keep all as well as overall survival. So we have to keep all of these various aspects of mind. But we’ll keep an eye on it, and we look at it as an upside. It’s a study that we wouldn’t have been able to fund ourselves at that time. And it’s in combination with PD-L1. So it’s going to be an interesting read out one way or the other.

Operator: Thank you. We have reached the end of our question-and-answer session. And with that, I would like to turn the floor back over to CEO, Dr. Jay Short for closing comments.

Jay Short: Well, I just appreciate everyone’s attendance, and we’ve got a very active fall here coming up, and we really look forward to speaking with everyone at meetings and other venues as we go forward; but thank you for your attention today.

Operator: Thank you. This concludes today’s teleconference. You may disconnect your lines at this time. Thank you for your participation.

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