Billionaire Stanley Druckenmiller’s Top 10 Stocks Picks with Huge Upside Potential

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1. Vaxcyte, Inc. (NASDAQ:PCVX)

Upside Potential as of April 11: 342.69%

Duquesne Capital’s Stake Value: $7.06 million

Number of Hedge Fund Holders: 50

Vaxcyte Inc. (NASDAQ:PCVX) develops vaccines to protect people from serious bacterial infections. It creates advanced vaccines using modern techniques to improve effectiveness, and their main products are vaccines for preventing pneumococcal diseases, such as VAX-31 and VAX-24. The firm’s end markets are global, with a focus on regions where these infections pose significant health risks.

In Q4 2024, Vaxcyte Inc. (NASDAQ:PCVX) announced positive topline results from its Phase 1/2 study of VAX-31 in 1,015 healthy adults aged 50 and older. The vaccine was well tolerated and demonstrated a safety profile similar to Prevnar 20® with robust immune responses for all 31 serotypes. For all 11 incremental serotypes unique to VAX-31, all three doses met the superiority criteria. At the VAX-31 high dose, average immune responses were greater for 18 of 20 serotypes compared to Prevnar 20®, with seven achieving statistically higher immune responses.

The company has received Breakthrough Therapy Designation from the FDA for VAX-31 for the prevention of invasive pneumococcal disease in adults. This designation provides the firm with access to all elements of the FDA’s Fast Track program and support for an efficient drug development process. It remains on track to initiate the VAX-31 adult Phase 3 pivotal, non-inferiority study by mid-2025, with topline data expected in 2026.

While we acknowledge the potential of Vaxcyte Inc. (NASDAQ:PCVX) as an investment, our conviction lies in the belief that AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. There is an AI stock that went up since the beginning of 2025, while popular AI stocks lost around 25%. If you are looking for an AI stock that is more promising than PCVX but that trades at less than 5 times its earnings check out our report about the cheapest AI stock.

READ NEXT: 20 Best AI Stocks To Buy Now and 30 Best Stocks to Buy Now According to Billionaires.

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