BrentSaunders: Yes. So thanks for the question. Look, clearly, it is – the product is owned by Novartis and is subject to the normal customary closing conditions, and we do expect that to close towards the end of the year. That being said, I think you have to look at the history of this product in the category. So this was a drug launched by Shire sold to Takeda sold to Novartis, and then somewhat openly held for sale for the last several months. So look, I think human nature, any sales force looks at something like this and probably there is a little bit lack of energy or enthusiasm in that group, that’s just human nature. And so we are excited to get the deal closed and look for better ways to talk about the therapeutic benefits to doctors.
We know it is a promotionally sensitive category. I put some data related to the category. There are roughly 38 million people in the United States diagnosed with dry eye disease, and yet only 1.4 million patients treating with a prescription solution. And so when I look at those dynamics, we’re very excited to have a differentiated treatment option for physicians to complement what we’re bringing with MIEBO. And then lastly, I’ll just – a little long winded. The most important metric I’m tracking while Novartis still is in ownership of the brand is TRx. And we saw about 4% TRx growth. And so to me, that is the most important metric until we close to track, and I think they’re doing a solid job there.
Douglas Miehm: Thank you.
Operator: Your next question is coming from Larry Biegelsen at Wells Fargo.
Larry Biegelsen: Good morning. Thanks for taking the questions. Congrats on a nice quarter here Brent and Sam. Two for me. One on MIEBO, one on 2024. So just to start on MIEBO, Brent, what would success look like? I mean we’ve looked at the XIIDRA launch as a benchmark. What are some of the puts and takes in your view of how adoption could be stronger or weaker, and would you be happy to say MIEBO ramp was about 50% of XIIDRA same time post launch. I mean XIIDRA been a successful product at about $500 million peak. So that’s my first question, just kind of how are you thinking about the ramp of MIEBO, and then I had a follow-up for Sam.
BrentSaunders: Sure. So as we look at MIEBO, I think looking at the XIIDRA launch is perhaps a little informative, but probably not right on. These are different products and different markets for dry eye disease. XIIDRA launched into what we would call the inflammatory associated dry eye category. That’s a very competitive category. You had – when it launched, you had a very strong RESTASIS, and since launch, you’ve had several other new entries and new products in late-stage development for inflammatory dry eye. MIEBO, on the other hand, is in a different part of the market for different patients and a different treatment modality, tear evaporation, and we are the only drug for tear evaporation. Most dry eye sufferers have tear evaporation related issues.
And so I do think we have an opportunity to be quite successful with this launch, and we’re very excited about it. In round numbers, I would say, I would be very disappointed if we didn’t see peak sales exceeding $350 million over time. But ramps take longer. Managed care access takes longer to work through. But I think we’re in a very good position with a great product.
Larry Biegelsen: That’s super helpful. Sam, obviously, you’re not giving guidance for 2024, but there are a lot of moving parts. And I’m just wondering if you could maybe provide a framework for how to think about 2024? What are some of the things to consider? XIIDRA, $400 million to $500 million in revenues. I think you’ve talked about that being about 10% accretive. I just want to confirm if that’s still true. Blink revenues, the MIEBO launch, the PROLENSA loss of exclusivity, and just to sum it up, the Street’s modeling about $1 in EPS right now next year versus, call it, $0.75 to $0.80 this year. Does that seem about right with all the moving parts? Is there anything you would highlight? I mean obviously, valuation is primarily based on ’24. So just hoping you could provide some framework there? Thank you.
SamEldessouky: There’s a lot to unpack in just one question. So let me step back and maybe just think about from a big picture framework. And I will start by – I’m not going to give guidance in 2024 today, I think we’re still early to do that. But there’s a couple of factors you have to think about the fundamentals of our business. And I will probably start and/or anchor in what we’ve seen here in the second quarter. We’ve seen strong performance in the business across all three segments. We’ve seen the demand in our portfolio is significant. So we are very excited about that. I would expect that momentum of the strong demand will continue with us, as we go forward into 2024. We’re also seeing that with the acquisition, we mentioned Blink and XIIDRA.
