Ardelyx (ARDX): RA Capital Management Boosts Stake to 7.7%

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SIGNATURE

After reasonable inquiry
and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Date: July 28, 2016
RA CAPITAL MANAGEMENT, LLC
By: /s/ Peter Kolchinsky

Peter Kolchinsky

Authorized Signatory

PETER KOLCHINSKY
/s/ Peter Kolchinsky
RA CAPITAL HEALTHCARE FUND, L.P.
By: RA Capital Management, LLC
Its: General Partner
By: /s/ Peter Kolchinsky

Peter Kolchinsky

Authorized Signatory

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