Page 2 of 7 – SEC Filing CUSIP No. 039697107 13G
1. Names of Reporting Persons.
I.R.S. Identification Nos. of above persons (entities only).
RA Capital Management, LLC
2. Check the Appropriate Box if a Member of a Group (See Instructions) (a) ¨ (b) ¨
3. SEC Use Only 4. Citizenship or Place of Organization Massachusetts
Number of
Shares
Beneficially
Owned by
Each Reporting
Person With 5. Sole Voting Power 0 6. Shared Voting Power 3,625,943 7. Sole Dispositive Power 0 8. Shared Dispositive Power 3,625,943
9. Aggregate Amount Beneficially Owned by Each Reporting Person
3,625,943
10. Check if the Aggregate Amount in Row (9) Excludes ¨
Certain Shares (See Instructions)
11. Percent of Class Represented by Amount in Row (9)
7.7%1
12. Type of Reporting Person (See Instructions)
IA
1 The reporting person is the beneficial owner of
3,457,718 shares of Common Stock, as well as warrants to acquire 168,225 shares of Common Stock, which together would constitute
approximately 7.7% of the issuer’s Common Stock if the warrants were exercised in full, following the issuance of 168,225
shares of Common Stock in respect of the fully-exercised warrants. The percentage calculation assumes that there are currently
47,230,378 outstanding shares of the Issuer, based on the Issuer’s 10-Q as filed with the Securities and Exchange Commission
(“SEC”) on May 9, 2016 and the Issuer’s 8-K as filed with the SEC on July 20, 2016.
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| CUSIP No. 039697107 | 13G | |
| 1. | Names of Reporting Persons.
RA Capital Management, LLC |
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions) | ||
| (a) | ¨ | ||
| (b) | ¨ | ||
| 3. | SEC Use Only | |
| 4. | Citizenship or Place of Organization Massachusetts | |
| Number of Shares Beneficially Owned by Each Reporting Person With | 5. | Sole Voting Power | 0 |
| 6. | Shared Voting Power | 3,625,943 | |
| 7. | Sole Dispositive Power | 0 | |
| 8. | Shared Dispositive Power | 3,625,943 | |
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person 3,625,943 | |
| 10. | Check if the Aggregate Amount in Row (9) Excludes ¨ Certain Shares (See Instructions) | |
| 11. | Percent of Class Represented by Amount in Row (9)
7.7%1 | |
| 12. | Type of Reporting Person (See Instructions) IA |
1 The reporting person is the beneficial owner of
3,457,718 shares of Common Stock, as well as warrants to acquire 168,225 shares of Common Stock, which together would constitute
approximately 7.7% of the issuer’s Common Stock if the warrants were exercised in full, following the issuance of 168,225
shares of Common Stock in respect of the fully-exercised warrants. The percentage calculation assumes that there are currently
47,230,378 outstanding shares of the Issuer, based on the Issuer’s 10-Q as filed with the Securities and Exchange Commission
(“SEC”) on May 9, 2016 and the Issuer’s 8-K as filed with the SEC on July 20, 2016.
