Aquinox Pharmaceuticals Inc (AQXP): Baker Bros. Advisors Pushes Stake to Over 45%

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SIGNATURE

After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true, complete and correct.

September 21, 2016

BAKER BROS. ADVISORS LP
By:  Baker Bros. Advisors (GP) LLC, its general partner
By: /s/ Scott L. Lessing
Name: Scott L. Lessing
Title: President
BAKER BROS. ADVISORS (GP) LLC
By: /s/ Scott L. Lessing
Name: Scott L. Lessing
Title: President
  /s/ Julian C. Baker
Julian C. Baker
  /s/ Felix J. Baker
Felix J. Baker

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