15. San Diego-Carlsbad, CA
Per Capita Personal Income: $53,298
U.S. Rank: 35
GDP: $220,573 millions
U.S. Rank: 16
San Diego is the 8th largest city in the United States and known as the “birthplace of California”. The largest contributor to the city’s economy is defense/military industry and tourism. Also, it is important to note that some experts have labeled San Diego as one of the best in the United States to start a small business.