Alnylam Pharmaceuticals, Inc. (ALNY): Eastern Capital Owns 3.8 Million Shares

 

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G/A

Under the Securities Exchange
Act of 1934
(Amendment No. 4)*

Alnylam Pharmaceuticals, Inc.

(Name of Issuer)

COMMON STOCK, $0.01
PAR VALUE PER SHARE

(Title of Class of Securities)

02043Q107

(CUSIP Number)

William Sullivan,
10 Market Street, #773 Camana Bay Grand Cayman, KY1-9006 CAYMAN ISLANDS, 345-640-3300

(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)

February 25, 2016

(Date
of Event which Requires Filing of this Statement)

Check
the appropriate box to designate the rule pursuant to which this Schedule is filed:
¨  Rule
13d-1(b)
☒  Rule
13d-1(c)
¨  Rule 13d-1(d)

^* The remainder of this cover page shall
be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any
subsequent amendment containing information which would alter disclosures provided in a prior cover page.

The information required on the remainder of this cover
page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”)
or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
see the Notes).