These are not huge quantities of plasma, but every batch is 4,400 liters. And if we can get more plasma, we can produce more, we’ve got more production slots available switching ASCENIV to the 4,400-liter scale, and it’s all falling into place. So I’d like the inflationary headwinds to subside just because it’s crazy out there. But it certainly has not been slow for our collection centers. So we’re really, really happy with the job they’re doing. And from what I can see, we’ve got good inventories of material, Elliot. So I don’t foresee any issue with us meeting or exceeding even the out-year revenue and financial targets that we’ve set for the business.
Operator: . And our next question comes from Kristen Kluska from Cantor.
Kristen Kluska: Congrats on a great 2022 and continued success, really, especially when you consider coming back from some of the hardest times of the pandemic and the macro environment we’re in. So I wanted to ask, given your initiatives to unlock new growth opportunities, Adam, you started to comment about ways you’re looking to measure and source more plasma from those with sufficient levels of titers to RSV. So I know there’s just a small percent of people who have these levels. But naturally, if your footprint is increasing across your centers, I would imagine that you’re collecting more of this plasma. So how could this initiative and some of these changes also help to consider some of your revenue goals and even potentially exceeding them?
Adam Grossman: Sure. Thanks for the continued support, and thanks for the good question, Kristen. I hope you guys are well. I think what we say in our public filings is roughly 10% of people have the titers that we’re looking for. What’s nice about collecting the majority of this plasma yourself — and look, we still work with Grifols. That supply contract is in good standing through mid-2027. We’ve got some other smaller collectors who we work with on high-titer to RSV plasma as well. But what I can say is I can’t force them to call this donor back and get that donor in a chair. I can force Brian and our plasma collection centers to spend in some time, spend some effort, get the donors who we know have high levels of neutralizing antibodies to RSV and get them to come in.
And we can target incentives. We can roll out the red carpet, whatever we need to do, but we have much more control over those donors that are coming into our own centers. So while 10% of people or less have the antibodies that we’re looking for, that doesn’t mean that only 10% of the plasma that we collect will be high-titer to RSV because we can manage which donors are coming into our centers. So it’s a science, it’s an art, however you want to view it, but these are special people. And we really take it very, very seriously, and we have targeted programs to bring these folks in. So we really think that having this control, and this was what we set out to do in 2020 when we embarked on the supply chain robustness, is take over the control.
And I don’t want to say that we can choose which bodies are in the donor bed that day, but we can certainly do our best to continue to call, motivate and incentivize the RSV high-titer donors to come back. Your other question was around some of the growth opportunities. And the 4,400 scale, as I talked about, certainly will expand access to more ASCENIV in the market. And obviously, we’ll open up more production slots to make any of our IG products. But we’re really excited about the potential yield enhancement initiatives. So we’re looking at taking some of our discard fractions. In our discard fractions, there is IG. And if we can unlock the ability to harvest some of this product — look, this will take some comparability work, this will take a submission to FDA, but we do feel that there could be a very, very modest investment.
